Inhibitory effect of honey on some bacterial infections

Nabhan Yassein, A; Najla,

	Inhibitory effect of honey on some bacterial infections
Diyala Journal For Pure Science
Article 1, Volume 7, Issue 3, 2011, Pages 227-241
Authors
a Nabhan Yassein;
Abstract
The antibacterial profiles of honey were examined against clinical isolates ofStaphyllococcus aureus and Pseudomonas aeruginosa. Agar well diffusion method was usedin the antibacterial susceptibility studies. This study revealed that the honey obtained fromAgricultural college of Baghdad University was effective against bacteria.The highestinhibitory zone of S. aureus reached to 20mm in diameter at 200 mg/ml of honeyconcentration but not affected on P. aeruginosa. Wounds were done in male mice by usingshaver and then infected with 0.1ml of both bacterial suspensions with concentration 108CFU/ml.Symptomes of infections were appeared after 24-48 hours. Three concentrations ofhoney were used (100,200 and 300) mg/ml for treatment of skin infections by using 0.1 ml ofhoney,also gentamycin ointment and normal saline were used. Symptomes of recovery basedon wound healing were noticed after 10,6,9,11 and 15 days for S. aureus and 12,8,13,15 and18 days for P. aeruginosa when treated with 100,200 and 300mg/ml of honey,gentamycin andnormal saline respectively. 200 mg/ml of honey concentration showed the best concentrationfor skin infection treatment. This study,therefore, suggest that honey could have strongbiocidal effect against S. aureus (both in vitro and in vivo) and against P. aeruginosa (invivo),therefore,have the potential effective role in the treatment of skin infection.
Keywords
honey on some bacterial infections

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