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A Comparative Study of Alkaline Phosphatase Levels in the Serum of Patients with End-Stage Renal Disease, and Viral Hepatitis At Dhi Qar, Iraq | ||
| Trends in Pharmaceutical Biotechnology | ||
| Volume 1, Issue 2, December 2023, Pages 24-30 PDF (2.25 M) | ||
| Document Type: Original article | ||
| DOI: 10.57238/tpb.2023.148536.1008 | ||
| Author | ||
| Haneen Mohammed Radhi* | ||
| College of Dentistry, University of Thi-Qar, Thi Qar 64001, Iraq. | ||
| Abstract | ||
| In recent years, the extent of liver damage by hemodialysis with hepatitis C is critical interest and debate. In this research, Patients on hemodialysis and those with normal renal function had their biochemical profile, liver histology, and symptoms of the hepatitis C virus examined and analyzed. Alkaline phosphatase enzyme (ALP), is linked to high levels of hepatitis and end-stage renal disease. In this study, patients with Hepatitis B virus (HBV) and thirty end-stage renal disease (ESRD) patients with Hepatitis C virus (HCV) were included. Gender, anticipated period of infection and age of infection were matched among ESRD patients. The aim of study is to measure and compare the serum levels of alanine aminotransferase (ALT), aspartate lipase (ALP), and aspartate aminotransferase (AST) in four groups: ESRD patients without hepatitis B, ESRD patients with hepatitis C, and healthy controls. The results demonstrated that hepatitis C patients with ESRD exhibited increases in their blood ALT and AST levels in contrast to hepatitis B patients with ESRD and the control group. Moreover, compared to chronic kidney disease (CKD) patients without hepatitis, individuals with ESRD had noticeably lower levels of these enzymes. The levels of Serum ALP were considerably greater in the hepatitis and ESRD groups than in the control group. Patients with HBV/HCV coinfection they often more vulnerable to liver-related morbidity and mortality compared to ESRD, HBV, or HCV patients. | ||
| Keywords | ||
| CKD; ESRD; AST; ALP; HCV; HBV | ||
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