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The Effect of Microneedling on Skin Histology: Review of Literature | ||
| Annals of the College of Medicine, Mosul | ||
| Volume 46, Issue 1, June 2024, Pages 114-119 PDF (442.6 K) | ||
| Document Type: Review Paper | ||
| DOI: 10.33899/mmed.2024.144268.1236 | ||
| Authors | ||
| Harith Ali Hasan Al-Nauimi* 1; Ashraf Abdulraheem Alsamadi2; Ahmed Hisham Qassim2 | ||
| 1Department of Anatomy, Histology and Embryology, College of Medicine, University of Mosul | ||
| 2Department of Anatomy, Histology and Embryology, College of Medicine, University of Mosul, Mosul, Iraq | ||
| Abstract | ||
| Aim: explore the advantages of using microneedling tenique for treating dermatological disorders. Background: The microneedling process has been expanded in the last decade, since it is considered as a safe, effective, low-cost and accessible aesthetic technique. It is a process of mechanical induced skin reconstruction. Microneedling is a technique compose of fine needles, which create a fine superficial skin perforations that initiate factors such as fibroblast growth factor (GF), platelet-derived factor and transforming GF α and β, which stimulate fibroblasts enabling them to form and reorganize new elastin as well as collagen fibers via a process of fibronectin matrix formation resulting in new skin tissues remodeling. There are many types of microneedling include: Roller microneedling device, it has a drum-like head with numbers of tiny needles; Electronic microneedling which is a pen-like instrument; Radio frequency microneedling device, which works as a microneedling pen plus bipolar radio frequency energy. Microneedling induces histological changes in the skin, such as mild epidermal hyperplasia, dermal deposition of extracellular glycosaminoglycans and fibrin, in addition to proliferation of keratinocytes and fibroblast, there are an increase in elastic material in mid and papillary dermis, marked thickening of skin dermis and improvement of collagen material. Conclusion: microneedling is advised for treatment of various skin diseases like facial scars, stretch marks, dyschromial conditions, rejuvenate photoaged skin, alopecia, actinic keratoses and pigmentary disorders. | ||
| Keywords | ||
| Microneedling; skin; histological changes; scar | ||
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