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Studying the effect of plant extracts on gram-positive and gram-negative pathogens: Review | ||
| Journal of University of Anbar for Pure Science | ||
| Volume 18, Issue 1, June 2024, Pages 76-85 PDF (704.23 K) | ||
| Document Type: Review Paper | ||
| DOI: 10.37652/juaps.2023.144339.1159 | ||
| Authors | ||
| Alaa S. Sadah Al-Halfi* ; Maher Zaki Faisal Al-Shammari; Souad Khalil Ibrahim | ||
| Department of Biology, College of Education Pure Science Ibn Al-Haitham, University of Baghdad, Baghdad, Iraq | ||
| Abstract | ||
| Gram-positive and Gram-negative antibiotic-resistant bacteria (called MDA) pose a continuing and ever-increasing threat to human health around the world, especially in poor countries. The aim of the study is to find alternatives to traditional antibiotics or extract effective compounds that work synergistically with or as an alternative to antibiotics. Many studies have proven the ability of plant extracts, especially the volatile oils in aromatic or medicinal plants such as Ginger and Thyme, to inhibit or kill negative bacteria such as Pseudomonas aeruginosa and gram-positive bacteria such as Staphylococcus aureus, which is resistant to antibiotics. It was found that these extracts consist of chemical compounds. Carbohydrate acids destroy and dissolve bacterial membranes and destroy the target cell. Bacterial colonies were diagnosed based on their morphological characteristics, such as the size, colour, edges and height of the colonies, their ability to ferment the sugar lactose, and their ability to produce mucus and hemolysin. Diagnosis of isolates using biochemical tests with three main tests. Molecular diagnosis is carried out by performing PCR tests and using (VITEK2) technology. The active compounds were extracted from ginger and thyme using various polar organic solvents, and it was found that virulence genes, such as enzymes, toxins, adhesive proteins, and cell surface proteins produced by S. aureus and other types of pathogenic bacteria, are responsible for the infections formed in people infected with this disease. | ||
| Keywords | ||
| MDA,,; ,،Gram-positive and Gram -negative pathogens,,; ,،Thyme,,; ,،Virulence genes,,; ,،Ginger | ||
| References | ||
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