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Hepatitis C Virus genotypes in Nineveh Governorate | ||
| The Medical Journal of Basrah University | ||
| Article 13, Volume 42, Issue 1, June 2024, Pages 99-107 PDF (308.92 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.33762/mjbu.2024.146721.1193 | ||
| Authors | ||
| Abdullah Zuhair Alyouzbaki* 1; Ayad Mohammed2; Barrak Al Obeidy3; Sohaib Issa4; Rashid Alsayyid4; waleed Husssien5 | ||
| 1college of medicine , university of mosul | ||
| 2Medical microbiology , public health laboratory in Mosul | ||
| 3Laboratory of medical biology, Alhadbaa Hospital for blood diseases and bone marrow transplantation | ||
| 4Public health laboratory in Mosul | ||
| 5Public health laboratory , Mosul | ||
| Abstract | ||
| Background: Hepatitis C virus (HCV) infection is considered a major health problem worldwide. Despite the availability of an effective direct-acting antiviral (DAA) therapy; 58 million people still have chronic HCV globally. HCV had 6 major genotypes; identification of specific genotypes linked to appropriate DAA selection. Aim of this study: To know the predominant HCV genotype in Nineveh governorate. Patients and Methods: This is a descriptive cross-sectional study conducted in public health laboratory in Nineveh from March 2022 to February 2023, 107 patients with HCV antibodies were included in this study, they underwent HCV real-time polymerase chain reaction (RT PCR) and genotyping, all those 107 patients had positive HCV antibody by enzyme-linked immunosorbent assay (ELISA). Results: From 107 patients with positive HCV antibodies, only 50 patients (46.7%) had positive HCV PCR, Genotype 4 is the most common HCV genotype in Nineveh (48 % and genotype 1a (26%) is the second common genotype, half of the current patients were young and HCV more common in male patients (62%). Conclusion: The most prevalent HCV genotype in Nineveh governorate is genotype 4 followed by genotype 1a. | ||
| Keywords | ||
| Keywords: Genotype; Hepatitis C Virus; Liver diseases | ||
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