The Association between Free Radicals and the Ovarian Functions: A Review

Khamees Abed, Sabea; Hadi Jasim, Husam; Ali Shahooth, Mohammed; A. Saud, Mustafa

	The Association between Free Radicals and the Ovarian Functions: A Review
Al-Anbar Journal of Veterinary Sciences
Volume 17, Issue 1, August 2024, Pages 11-17 PDF (710.35 K)
Document Type: Review Paper
Authors
Sabea khamees Abed^* ¹; Husam Hadi Jasim¹; Mohammed Ali Shahooth²; Mustafa A. Saud
¹Departement of Pharmacology and Physiology, College of Veterinary Medicine, University of Fallujah.
²Departement of Animal Production, College of Agriculture, University of Anbar.
Abstract
Metabolites of oxygen are called reactive oxygen species (ROS). They are constantly synthesized by healthy cells and are a consequence of aerobic respiration and are necessary for proper cellular function. These species (ROS) cause oxidative stress as a result of generation exceeding the capabilities of the antioxidant system to neutralize it. It is a bifurcating factor in controlling the reproductive system of females, as it can influence various physiological activities or contribute to infertility in females. The current review notes that several ovarian function processes, including reactive oxygen species, have a major impact on follicular formation, ovulation, and corpus luteum function. Scavenging mechanisms also occur. However, the review concentrates on the detrimental impact that elevated ROS production has on the female reproductive system. This review concludes that free radicals play a variety of roles in ovarian function and that excess has negative effects on the female reproductive system.
Keywords
Reactive Oxygen Species; Oxidative Stress; Ovarian Function

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