Protective Effect of Acetyl L-Carnitine on Rat Spermatogenesis Defects Induced by Lead Acetate

UL-Rahman Muhammed Ibrahim, Abd; Osama Husain, Enas

	Protective Effect of Acetyl L-Carnitine on Rat Spermatogenesis Defects Induced by Lead Acetate
Al-Anbar Journal of Veterinary Sciences
Volume 16, Issue 1, August 2023, Pages 70-79 PDF (1.05 M)
Authors
Abd UL-Rahman Muhammed Ibrahim; Enas Osama Husain
Abstract
In this study the influences of the ameliorative effects of Acetyl-L-carnitine when exposed to lead acetate on functional aspects in spermatogenesis process in testes of albino male rats was studied, 24 male albino rats weight 178-250 g were randomly distributed into four groups, 6 rats in each, the control group received distilled water orally, Treatment 1 lead acetate group received 10mgkg body weight orally, Treatment 2 acetyl L-carnitine(ALCAR) group received 100mgkg body weight orally, and Treatment 3 lead acetate and acetyl L-carnitine group received 10mgkg body weight and 100mgkg body weight orally respectively. After the end of the experiment the weight of sexual organs were taken, in addition, the total sperm count number, and percentage of dead, live, with abnormal spermatozoa also have been calculated. Result showed that the total sperm count in lead acetate group was decreased in compared with control and ALCAR groups. The lead acetate with ALCAR showed increased in total sperm count and live sperm percentage in compared with control and ALCAR groups. Dead and abnormal sperm percentage increased in lead acetate group and in lead with ALCAR groups in compared with control and ALCAR groups.
Keywords
Lead acetate acetyl L-carnitine; Spermatogenesis; Rats

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