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Study the physiological effects of finasteride (prostacare) on some reproductive parameters in male rats.(Rattus- Rattus). | ||
| Al-Anbar Journal of Veterinary Sciences | ||
| Volume 13, Issue 1, August 2020, Pages 59-67 PDF (1.3 M) | ||
| Document Type: Research Paper | ||
| DOI: 10.37940/AJVS.2020.13.1.7 | ||
| Authors | ||
| Yasmeen J. Mohammed* ; Zainab W. Khudair | ||
| College of Veterinary Medicine, University of Basrah | ||
| Abstract | ||
| This study was conducted in the veterinary medicine college animal house and aimed to investigate the effect of finasteride (prostacare) on male reproductive system in albino male rats (Rattua-Rattus). Thirty six mature male rats with body weight 200-210 g and age 8 weeks of were randomly divided into three groups (12 animal each group). The first group was considered as control group and adminstreted orally normal salin (9%N.S)during the experimental 30 days , the second group was administrated finasteride(0.016mg) during the experimental(30)days.and the third group was administrated finasteride(0.032mg) during the experimental 30 days. The results showed a significant decrease in the sperm count ,sperm motility ,live sperm and increase in dead sperm percentage as well as a significant decrease in the level of reproductive hormones (testosterone, LH and FSH) in treated group with finasteride compared with control group , from this study it was concluded that the finasteride has sever side effect on fertility in albino male rats (Rattus-Rattus). | ||
| Keywords | ||
| Sildenafil; Histopathological; Kidney; Male Rat | ||
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