Histological structure in immune suppression male micebrain and other natural experimentally infected with Candida glabrata

Mezher, Milad Adnan

	Histological structure in immune suppression male micebrain and other natural experimentally infected with Candida glabrata
Al-Anbar Journal of Veterinary Sciences
Volume 11, Issue 2, August 2018, Pages 1-8 PDF (1.12 M)
Document Type: Research Paper
Author
Milad Adnan Mezher
College of Education for Pure Science/ University of Tikrit
Abstract
The current study included analysis the brain tissue structure after exposure to experimentally infection with Candida glabrata in BALB male mice which isolated from patients attending Tikrit Teaching Hospital suffering from Candimia (38 male, 25 female) aged (82-15 years). The results indicated different histopathological changes in the brains immunosuppressed studied mice, the results represented congestion of blood vessels of the five cerebral cortex layers, as well as the foamy appearance of the matrix of molecular layer of the cerebral cortex. In contrast the non-immunosuppressed mice group included histological changes represented with rupture of the pia matter, as well as shrinking or shrinkage of the six-layer cells of the adjoining cortex of the pia matter and the emergence of vacuoles around cells and nerve fibers on a large scale. The group of mice immunosuppressed show pathological changes represented with atrophy of pyramidal cells and glial cells in all layers of the cerebral cortex, as well as the spongy-like appearance of the brain medulla, compared with the control group.
Keywords
Candida glabrata; brain; immunologically inhibitory; histological changes

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