Al-Tameemi, H., Najem, H. (2024). Effect of determining protective antibodies on the efficacy of two types Newcastle disease vaccines in broilers. , 23(1), 57-60. doi: 10.29079/qjvms.2024.185133
Hassan M. Al-Tameemi; Harith Abdulla Najem. "Effect of determining protective antibodies on the efficacy of two types Newcastle disease vaccines in broilers". , 23, 1, 2024, 57-60. doi: 10.29079/qjvms.2024.185133
Al-Tameemi, H., Najem, H. (2024). 'Effect of determining protective antibodies on the efficacy of two types Newcastle disease vaccines in broilers', , 23(1), pp. 57-60. doi: 10.29079/qjvms.2024.185133
Al-Tameemi, H., Najem, H. Effect of determining protective antibodies on the efficacy of two types Newcastle disease vaccines in broilers. , 2024; 23(1): 57-60. doi: 10.29079/qjvms.2024.185133

Effect of determining protective antibodies on the efficacy of two types Newcastle disease vaccines in broilers

Al-Qadisiyah Journal of Veterinary Medicine Sciences
Volume 23, Issue 1, May 2024, Pages 57-60    PDF (180.29 K)
Document Type: Research Paper
DOI: 10.29079/qjvms.2024.185133
Authors
Hassan M. Al-Tameemi* 1; Harith Abdulla Najem2
1Department of Microbiology, College of Veterinary Medicine, University of Basrah, 61004, Iraq
2Department of Pathology and Poultry diseases, College of Veterinary Medicine, University of Basrah, 61004, Iraq
Abstract
A total of 60 one-day-old Ross broiler chicks were used in this investigation. The birds were categorized into four groups, with each group including 15 birds. Group A was administered a 0.5 ml dosage of the LaSota live vaccination against Newcastle disease using the oral approach on the first day of their lives, using a 1 ml syringe. On the other hand, Group B got the dead vaccine by a subcutaneous injection. Group C was administered two distinct forms of vaccine: live and dead, whilst Group D was designated as the control group. On the 35th day, the birds were euthanized in order to obtain blood samples for the purpose of studying the impact of various vaccination types on the immunological response to the ND vaccine. The response was evaluated using an ELISA test. The findings demonstrated statistically significant differences (P≤0.05) in antibody titers between group B and the control group. Additionally, groups C and A exhibited substantial increases (p<0.05) in antibody titers compared to the control group, which experienced a significant drop (P≤0.05) in antibody titers. Overall, the results indicated that the inactivated vaccine produced a higher level of antibodies. However, further evidence demonstrated that administering a live virus vaccination on the first day after birth resulted in the suppression of the mother's immune response by the vaccine virus. Hence, it is crucial to ascertain the antibody titer prior to determining the vaccine's course.
Keywords
Newcastle disease; Vaccines; Antibody Titers, broilers
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