Al-Shakerji, A., Al-Mahdawi, A., Al Shammary, S. (2024). Clinical Patterns of Guillain-Barré Syndrome Associated with the COVID-19 Pandemic. , 23(4), 466-471. doi: 10.52573/ipmj.2024.141037
Ali Samir Y. Al-Shakerji; Akram Mohammed Al-Mahdawi; Safaa Hussein Al Shammary. "Clinical Patterns of Guillain-Barré Syndrome Associated with the COVID-19 Pandemic". , 23, 4, 2024, 466-471. doi: 10.52573/ipmj.2024.141037
Al-Shakerji, A., Al-Mahdawi, A., Al Shammary, S. (2024). 'Clinical Patterns of Guillain-Barré Syndrome Associated with the COVID-19 Pandemic', , 23(4), pp. 466-471. doi: 10.52573/ipmj.2024.141037
Al-Shakerji, A., Al-Mahdawi, A., Al Shammary, S. Clinical Patterns of Guillain-Barré Syndrome Associated with the COVID-19 Pandemic. , 2024; 23(4): 466-471. doi: 10.52573/ipmj.2024.141037

Clinical Patterns of Guillain-Barré Syndrome Associated with the COVID-19 Pandemic

Iraqi Postgraduate Medical Journal
Article 14, Volume 23, Issue 4, October 2024, Pages 466-471    PDF (584.03 K)
Document Type: Research Paper
DOI: 10.52573/ipmj.2024.141037
Authors
Ali Samir Y. Al-Shakerji* 1; Akram Mohammed Al-Mahdawi2; Safaa Hussein Al Shammary3
1Lecturer at Mosul Medical College
2Chairman of the Scientific Iraqi Council of Neurology
3Assistant Professor at Mustansiriyah Medical College
Abstract
Clinical Patterns of Guillain-Barré Syndrome Associated with the COVID-19 Pandemic
Background: Guillain Barré Syndrome is an autoimmune disease, with progressive weakness and areflexia, it can be triggered due to antigenic mimicry, and the association of COVID-19 and GBS cases throughout the pandemic has been reported worldwide.
Objective: to identify the clinical patterns of GBS associated with COVID-19 and its neurophysiological variants.
Method: (51) patients were collected during 2021 who were admitted to Baghdad Medical City and Neuroscience Hospital, and diagnosed with GBS according to the Asbury criteria, all of them had serological or radiological evidence of current or recent COVID-19 infection, the neurophysiological study was done for all of them and variants were identified.
Results: males were (56.9%), half of GBS cases were presented in late spring after the peak of the second COVID-19 wave, the mean time interval between antecedent COVID-19 and GBS onset was 3.45 weeks, (82.4%) was ascending pattern, (5.9%) paraparetic, (5.9%) bilateral facial with distal paraesthesia, about (64.7%) had the demyelinating variant on Neurophysiological study, axonal in (29.4%) and equivocal in (5.9%).
Conclusion: Despite the limitations of our study, being a descriptive cross-sectional one, it represents the first snapshot of the relationship between COVID-19 and GBS in a large cohort of patients in Iraq, the classical ascending pattern is the most common clinical pattern associated with COVID-19 and demyelinating variant in neurophysiological studies.
Keywords
Guillain Barré Syndrome,,; ,،COVID-19,,; ,،GBS variants,,; ,،Neurophysiological pattern,,; ,،Neurological Complications
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