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Extracting alkaloids from medicinal herbs and studying their biological effectiveness against Staphylococcus aureus | ||
| Journal of University of Anbar for Pure Science | ||
| Volume 18, Issue 2, December 2024, Pages 139-145 PDF (1.05 M) | ||
| Document Type: Research Paper | ||
| DOI: 10.37652/juaps.2024.148662.1231 | ||
| Authors | ||
| Abdulhakeem Dahham Hussein* 1; Huthaifa AbdulRahman Talib2; Maha Amar Ibrahim3; Fatima Ammar Saleh3; Heba Nazim Ali3 | ||
| 1College of Applied Science-University of Fallujah | ||
| 2Department of Applied Chemistry, College of Applied Science, University of Fallujah. fallujah, Iraq | ||
| 3Department of Applied Chemistry, College of Applied Science, University of Fallujah, Fallujah, Iraq | ||
| Abstract | ||
| Due to the fact that they are more readily available and less expensive compared to contemporary medications, medicinal herbs are used extensively throughout society. Numerous phytochemicals with demonstrated or potential biological activity are recognized; however, the presence of numerous distinct chemical substances in a single plant reduces the effectiveness of employing the entire plant. Preventing assessing the effects of these substances, which are present in a broad range of plants, in a thorough scientific investigation to ascertain their safety and efficacy. The objective of this research was to quantify the alkaloids present in the aqueous extract of ten varieties of medicinal plants that are found in local markets and examine their biological efficacy in combating Staphylococcus aureus bacteria. The results indicated that, at 124.9 µg/gm, the chamomile plant's (Matricaria chamomilla) aqueous extract had the highest concentration of alkaloids, succeeded by the fenugreek plant's (Trigonella foenum-graecum) extract at 94.5 µg/gm. The lowest concentration of alkaloids in ginger (Zingiber officinale) extract was 5.7 µg/gm. biological efficacy experiments showed that the Cucurbita extract did not show any inhibition against bacteria at all concentrations, while the extracts of Piper nigrum, Nigella sativa, and Trigonella foenum-graecum showed inhibition against bacteria at all concentrations. As for the rest of the extracts, their effect varied depending on the concentrations, as the bacteria showed resistance with increasing dilution. | ||
| Keywords | ||
| Alkaloids; Biological activity; Medicinal herbs; Staphylococcus aureus | ||
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