Shareef, M. (2025). Effect of yeast supplemented with selenium or zinc on some antioxidant indices and liver and kidney functions in local Iraqi goats. , 16(1), 191-195. doi: 10.58928/ku25.16126
Mohanad Amir Shareef. "Effect of yeast supplemented with selenium or zinc on some antioxidant indices and liver and kidney functions in local Iraqi goats". , 16, 1, 2025, 191-195. doi: 10.58928/ku25.16126
Shareef, M. (2025). 'Effect of yeast supplemented with selenium or zinc on some antioxidant indices and liver and kidney functions in local Iraqi goats', , 16(1), pp. 191-195. doi: 10.58928/ku25.16126
Shareef, M. Effect of yeast supplemented with selenium or zinc on some antioxidant indices and liver and kidney functions in local Iraqi goats. , 2025; 16(1): 191-195. doi: 10.58928/ku25.16126

Effect of yeast supplemented with selenium or zinc on some antioxidant indices and liver and kidney functions in local Iraqi goats

Kirkuk University Journal for Agricultural Sciences (KUJAS)
Volume 16, Issue 1, March 2025, Pages 191-195    PDF (335.76 K)
Document Type: Research Paper
DOI: 10.58928/ku25.16126
Author
Mohanad Amir Shareef*
Department of Accommodation Affairs– headquarter- University of Anbar
Abstract
The purpose of the research was to investigate the effect of yeast supplemented with selenium or zinc on the antioxidant profile of local Iraqi goats. The study utilized seventeen female goats with an average body weight (BW) of 37.5 ± 2.5 kg and an average age of 2-2.5 years. The animals were randomly assigned to three groups: group I contained five goats, while groups II and III contained six goats. The control group (Group I) was not treated, while Group II was given a dose of selenium-supplemented yeast (Saccharomyces cerevisiae-selenium) at 0.03 g/kg/BW. Group III was offered a dose of zinc-supplemented yeast (Saccharomyces cerevisiae-zinc) at 0.2 g/kg/BW. The samples were administered orally to the animals for 45 days after being dissolved in 30 ml of distilled water. The changes in the level of liver and antioxidant enzymes were determined by collecting blood samples from the jugular vein on the first day and the 45th day. The result showed the Y+Se and Y+Zn treatments significantly reduced malondialdehyde, AST, and ALT in comparison to the control treatment (P < 0.05). However, the GPx levels of the animals that received the treatment diets increased. In both treatment treatments, there was a significant decrease in Creatinine and Urea. The treatments exhibited decreased indications of globulin and albumin in comparison to the control treatment. In conclusion, the results suggest that the serum antioxidant activity of goats was not only improved but also the lipid peroxidation was reduced by dietary yeast supplemented with selenium (Saccharomyces cerevisiae-selenium).
Keywords
Saccharomyces cerevisiae; Zinc; Selenium; enzymes; goats
References
  • Ahsan U., Kamran, Z., Raza, I., Ahmad, S., Babar, W., Riaz, M. and Iqbal, Z. 2014. Role of selenium in male reproduction—A review. Animal Reproduction Science.146(1-2):55.
  • Howard M.T. and Copeland, P.R. 2019. New directions for understanding the codon redefinition required for selenocysteine incorporation. Biological Trace Element Research.192(1):18.
  • Shi L., Xun, W., Yue, W., Zhang, C., Ren, Y., Shi, L., Wang, Q., Yang, R. and Lei, F. 2011. Effect of sodium selenite, Se-yeast and nano-elemental selenium on growth performance, Se concentration and antioxidant status in growing male goats. Small Ruminant Research. 96(1):49.
  • Shen X. and Song, C. 2021. Responses of Chinese merino sheep (Junken Type) on copper-deprived natural pasture. Biological Trace Element Research.199:989.
  • Shareef M., Mohammed, T. and muneeb Alrawi, H. 2019. Effect of Yeast (Saccharomyces cerevisiae) Enhanced with Selenium or Zinc on the Hematological Characteristics in Iraqi Does. Al-Anbar Journal of Veterinary Sciences.12(2):75.
  • Shareef M., Mohammed, T. and Alrawi, H. Impact of Saccharomyces cerevisiae enriched with Selenium or Zinc on reproductive performance, estrogen and progesterone hormone in local Iraqi female goats. IOP Conference Series: Earth and Environmental Science: IOP Publishing; 2021, p. 012095.
  • Zhang R., Yang, Y., Min, M. and Li, Y. 2022. Effect of dietary supplements on Se bioavailability: A comprehensive in vitro and in vivo study. Ecotoxicology and Environmental Safety. 231:113193.
  • Mojadadi A., Au, A., Salah, W., Witting, P. and Ahmad, G. 2021. Role for selenium in metabolic homeostasis and human reproduction. Nutrients.13(9):3256.
  • Aghwan Z.A., Sazili, A.Q., Kadhim, K.K., Alimon, A.R., Goh, Y.M. and Adeyemi, K.D. 2016. Effects of dietary supplementation of selenium and iodine on growth performance, carcass characteristics and histology of thyroid gland in goats. Animal Science Journal. 87(5):690.
  • Nutrient requirements of small ruminants: sheep, goats, cervids, and new world camelids: National Academy Press; 2007.
  • Duncan D.B. 1955. Multiple range and multiple F tests. Biometrics.11(1):1.
  • Shi L., Ren, Y., Zhang, C., Yue, W. and Lei, F. 2017. Effects of maternal dietary selenium (Se-enriched yeast) on growth performance, antioxidant status and haemato-biochemical parameters of their male kids in Taihang black goats. Animal Feed Science and Technology. 231:67.
  • Pavlata L., Misurova, L., Pechova, A. and Dvorak, R. 2011. The effect of inorganic and organically bound forms of selenium on glutathione peroxidase activity in the blood of goats. Veterinary Medicine – Czech. 56(2):75-81 | DOI: 10.17221/1576-VETMED
  • Aremmt M.K., Mohammed, T. and Alrawi, S.T.J. 2019. Effect of Yeast (Saccharomyces cerevisiae) Supported by Selenium and Zinc on Lipid Profile of Local Sheep Males. Al-Anbar Journal of Veterinary Sciences. 12(1).
  • Malakouti M., Kataria, A., Ali, S.K. and Schenker, S. 2017. Elevated liver enzymes in asymptomatic patients–what should I do? Journal of Clinical and Translational Hepatology. 5(4):394.
  • Yang Y., Wang, H., Guo, Y., Lei, W., Wang, J., Hu, X., Yang, J. and He, Q. 2016. Metal ion imbalance-related oxidative stress is involved in the mechanisms of liver injury in a rat model of chronic aluminum exposure. Biological Trace Element Research.173:126.
  • Kholif A., Abdo, M., Anele, U., El-Sayed, M. and Morsy, T. 2017. Saccharomyces cerevisiae does not work synergistically with exogenous enzymes to enhance feed utilization, ruminal fermentation and lactational performance of Nubian goats. Livestock Science. 206:17.
  • Shareef A., Al-Rawi, F., Omar, A. and Alrawi, M. 2023. Effect of Saccharomyces cerevisiae Fortified with Selenium on the Hematological and Some Biochemical Traits of Local Iraqi Goat. Archives of Razi Institute.78(4):1213.
  • El-Ratel I.T., El-Kholy, K.H., Elgmmal, S.M., Fouda, S.F., Abdel-Khalek, A.-K.E., Hassan, M.A., Azzam, M.M., Alagawany, M. and Lestingi, A. 2025. The synergetic effect of selenium or zinc oxide nanoparticles with chromium on mitigating thermal stress for sustainable production and improving antioxidant capacity and inflammatory cytokines of growing rabbits. Archives Animal Breeding. 68(1):43.
  • Mousaie A. 2021. Dietary supranutritional supplementation of selenium-enriched yeast improves feed efficiency and blood antioxidant status of growing lambs reared under warm environmental condition. Tropical Animal Health and Production. 53(1):138.
  • Alberghina D., Casella, S., Vazzana, I., Ferrantelli, V., Giannetto, C. and Piccione, G. 2010. Analysis of serum proteins in clinically healthy goats (Capra hircus) using agarose gel electrophoresis. Veterinary Clinical Pathology. 39(3):317.
  • Alimohamady R., Aliarabi, H., Bruckmaier, R.M. and Christensen, R.G. 2019. Effect of different sources of supplemental zinc on performance, nutrient digestibility, and antioxidant enzyme activities in lambs. Biological Trace Element Research.189:75.
  • Zhang C., Zhang, J., Yu, Z., Zhou, G. and Yao, J. 2022. Effects of supplementation with Saccharomyces cerevisiae products on dairy calves: A meta-analysis. Journal of Dairy Science. 105(9):7386.
 

 

Statistics
Article View: 418
PDF Download: 279


Journal Management System. Powered by iJournalPro.com