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Obesity and Insulin Resistance. | ||
| Rafidain Journal of Science | ||
| Volume 34, Issue 1, March 2025, Pages 100-109 PDF (663.35 K) | ||
| Document Type: Review Paper | ||
| DOI: 10.33899/rjs.2025.186499 | ||
| Authors | ||
| Rana Suhail Al-Juwary1; Haitham L. Al-Hayali2 | ||
| 1Biology Dept. /College of Science / Mosul University | ||
| 2Department of Biology/ College of Science/ Mosul University | ||
| Abstract | ||
| Insulin resistance and obesity are two health disorders associated with decreased insulin action, weight gain, and body fat accumulation. These two conditions can possess a significant effect on health and raise the chronic disease risk. There is a close relationship between obesity and insulin resistance, as people who suffer from obesity possibly develop insulin resistance. Excess body fat causes excess fatty tissue around vital organs like the pancreas and liver, hindering their insulin response. blood sugar high levels lead for type 2 diabetes risk. When the body is unable to use insulin effectively, resistance occurs resulting in high blood sugar levels. Several factors may play a role in the development of insulin resistance, including hormones secreted by adipose tissue, like adiponectin, which is useful for enhancing insulin sensitivity. However, its levels decrease in people who suffer from overweight and obesity, and thus their resistance to insulin increases, as well the hepatonctin, which is the hormone secreted by the liver and has a role in controlling blood sugar levels and metabolism. Additionally, obesity increases the risk of developing many other diseases that can be enhanced by the existence of insulin resistance, so it is important to monitor and manage weight properly to prevent these conditions. Regulating insulin resistance and obesity requires lifestyle changes like regular physical activity and eating healthy, balanced foods. In some cases, you may need drug or insulin therapy to control blood sugar levels and improve the body's response to insulin. | ||
| Keywords | ||
| Insulin; resistance; obesity; hormones; diabetic | ||
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