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New Modulation of Fluoride Remineralization Against Dental Caries: an in Vitro Study | ||
| Al-Rafidain Dental Journal | ||
| Article 12, Volume 25, Issue 2, September 2025, Pages 390-401 PDF (687.99 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/rdenj.2023.140963.1210 | ||
| Authors | ||
| Mohammed H. AL-Shaibani* 1; Maha T. Al-Saffar2; Abdulsattar S Mahmood* 3 | ||
| 1Ministry of health, Karbala health director, Centre Sector, Karbala, Iraq | ||
| 2Department of Basic dental sciences/College of Dentistry/ University of Mosul/ Iraq | ||
| 3Department of Oral Diagnosis, College of Dentistry, University of Mosul, Iraq | ||
| Abstract | ||
| This study aims to assess the local application of a novel fluoride supplement modification, achieved by dissolving fluoride tablets in deionized water, to achieve concentrations of 2500 ppm on demineralized tooth surfaces, thereby demonstrating its effectiveness as a remineralizing agent. Materials and Methods: 10 permanent molars were employed. Each tooth is enrolled in Teflon tape, and only the enamel of the occlusal surface is exposed to a demineralizing solution (acid etch) for 45 seconds in vitro. The teeth are then randomly assigned to two groups: Group 1 is treated with distilled water, and Group 2 is treated with a sodium fluoride solution. All groups except the control baseline group were treated with their respective remineralizing solutions for 10 days. Vickers' Microhardness Number (VHN) and Densometric X-Ray Analysis were completed at baseline, following demineralization, and subsequently 10 days after remineralization. Results: Densometric X-ray analysis and Microhardness Number (VHN) showed a remineralizing effect of sodium fluoride solution on enamel density and surface hardness after remineralization, with a significant difference observed after 10 days (p ≤ 0.05). The mean value in the group treated with sodium fluoride solution was higher than the recorded mean value for the group treated with distal water. Conclusion: Sodium fluoride solution is considered an effective remineralizing agent, significantly increasing enamel density and surface hardness. | ||
| Keywords | ||
| Densometric analysis; Fluoride solution; Microhardness; Remineralization | ||
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