Evaluating the role of arginine deaminase and its relationship with the development of diabetes in patients with non-alcoholic fatty liver disease

Rashed, Sukayna Hussain; Abdulla, Haala Tareq

doi:10.33899/berj.2025.187024

	Evaluating the role of arginine deaminase and its relationship with the development of diabetes in patients with non-alcoholic fatty liver disease
College Of Basic Education Research Journal
Volume 21, Issue 1, March 2025, Pages 605-633 PDF (720.3 K)
Document Type: Research Paper
DOI: 10.33899/berj.2025.187024
Authors
Sukayna Hussain Rashed^* ¹; Haala Tareq Abdulla²
¹جامعة الموصل/كلية العلوم/ قسم الكيمياء
²Senior Chief Chemist/ Ibn Sina Teaching Hospital/ Nineveh Health Department/ Mosul/ Iraq
Abstract
The study included the results obtained from examining (160) samples of blood serum for two groups: the control group, which included (80) samples, and the group of patients with non-alcoholic fatty liver disease (NAFLD), which included (80) samples. The groups were divided according to age into two age groups that included (less than 45) and (More than 45 years) and according to body mass index into obese (BMI greater than 25) and non-obese (BMI between 18 and 25) and according to gender into females and males. In addition to classifying patients into two groups: a group of treated patients and a group of newly diagnosed and untreated NAFLD patients, the study included estimating the activity of the enzyme arginine deaminase type 4 (ADI4) and the levels of some biochemical variables, which included total cholesterol T.C., triglycerides TG, and high-density lipoprotein cholesterol HDL-C, low-density LDL-C, very low-density VLDL-C, and glycated hemoglobin HbA1c. The results indicated an inverse relationship between the activity of ADI4 and HbA1c.
Keywords
NAFLD; الكوليستيرول الكلي; ADI4; HbA1c

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