Almashhadani, H., Al-Mahdawi, A. (2025). Language deficit in non-dominant hemisphere stroke patients. , 24(2), 218-229. doi: 10.52573/ipmj.2025.147403
Huda Sabeeh Almashhadani; Akram Mohammed Al-Mahdawi. "Language deficit in non-dominant hemisphere stroke patients". , 24, 2, 2025, 218-229. doi: 10.52573/ipmj.2025.147403
Almashhadani, H., Al-Mahdawi, A. (2025). 'Language deficit in non-dominant hemisphere stroke patients', , 24(2), pp. 218-229. doi: 10.52573/ipmj.2025.147403
Almashhadani, H., Al-Mahdawi, A. Language deficit in non-dominant hemisphere stroke patients. , 2025; 24(2): 218-229. doi: 10.52573/ipmj.2025.147403

Language deficit in non-dominant hemisphere stroke patients

Iraqi Postgraduate Medical Journal
Article 11, Volume 24, Issue 2, April 2025, Pages 218-229    PDF (437.35 K)
Document Type: Research Paper
DOI: 10.52573/ipmj.2025.147403
Authors
Huda Sabeeh Almashhadani* 1; Akram Mohammed Al-Mahdawi2
1Medical city
2Chairman of the Scientific Iraqi Council of Neurology
Abstract
Background: Despite the long history of research favoring the left hemisphere is dominant for language processing in most right-handed subjects. There is accumulating evidence that the right hemisphere contributes to language.

Aim: evaluate language deficits in right hemisphere stroke survivors so they will have the opportunity to be tested for deficits and offered compensatory strategies.

Patient and methods: comparative cross-sectional design, right-handed patients from 3 hospitals and a physiotherapy Centre in Iraq, aged (38-75 years), each had either right or left hemispheric stroke, patients with bilateral hemispheric stroke and who are not sufficiently clinically stable to be approached were excluded, and control group of neurologically healthy participant. we used the quick aphasia test for both patients and control groups, data collected between April 2022 and February 2023.

Results: we included 40 patients, 20 had right hemispheric stroke and 20 had left hemispheric stroke, and 20 neurologically healthy control group. mean age for patients was 58.2 years, aphasia was found in 30% of right hemispheric stroke patients and 35 % of left hemispheric stroke patients. Sentence comprehension was the most often impaired task for both left hemispheric stroke patients with mean score 7.19(SD = 2.36) and right hemispheric stroke patients with mean score of 8.07 (SD = 1.64). the difference in mean for word comprehension between right hemispheric stroke patients 9.58 (SD = 0.83) and control group (10 SD 0) was statistically significant with p value (0.03). grammatical construction was impaired more for the left hemispheric stroke patients with mean score 8.95(SD = 1.49) than the right hemispheric stroke patients with mean score 9.41 (SD = 0.6).

conclusion: right hemisphere has important role in language which can be affected by stroke so it can be vital to be looked for so adaptations can be done for better life for those patients.
Keywords
aphasia; language; non-dominant; right hemisphere; stroke
References
  1. Harrington A. Medicine, mind, and the double brain: A study in nineteenth century thought. Princeton University Press; 1989 Jan 21
  2. Lindell AK. In your right mind: Right hemisphere contributions to language processing and production. Neuropsychology review. 2006;16:131-48.
  3. Hartwigsen G, Baumgaertner A, Price CJ, Koehnke M, Ulmer S, Siebner HR. Phonological decisions require both the left and right supramarginal gyri. Proceedings of the National Academy of Sciences. 2010;107:16494-99.
  4. Sollmann N, Tanigawa N, Ringel F, Zimmer C, Meyer B, Krieg SM. Language and its right-hemispheric distribution in healthy brains: an investigation by repetitive transcranial magnetic stimulation. NeuroImage. 2014;102:776-88.
  5. Crinion J, Price CJ. Right anterior superior temporal activation predicts auditory sentence comprehension following aphasic stroke. Brain 2005;128:2858–71.
  6. Thiel A, Habedank B, Herholz K, Kessler J, Winhuisen L, Haupt WF, et al. From the left to the right: how the brain compensates progressive loss of language function. Brain Lang 2006; 98: 57–65.
  7. Forkel SJ, Thiebaut de Schotten M, Dell’Acqua F, Kalra L, Murphy DG, Williams SC, et al. Anatomical predictors of aphasia recovery: a tractography study of bilateral perisylvian language networks. Brain 2014; 137: 2027–39.
  8. Xing S, Lacey EH, Skipper-Kallal LM, Jiang X, Harris-Love ML, Zeng J, et al. Right hemisphere grey matter structure and language outcomes in chronic left hemisphere stroke. Brain 2016;139:227–41.
  9. Nardo D, Holland R, Leff AP, Price CJ, Crinion JT. Less is more: neural mechanisms underlying anomia treatment in chronic aphasic patients. Brain. 2017;140:3039-54.
  10. Hartwigsen G, Saur D, Price CJ, Ulmer S, Baumgaertner A, Siebner HR. Perturbation of the left inferior frontal gyrus triggers adaptive plasticity in the right homologous area during speech production. Proceedings of the National Academy of Sciences. 2013;110:16402-7.
  11. Ralph MA, Jefferies E, Patterson K, Rogers TT. The neural and computational bases of semantic cognition. Nature Reviews Neuroscience. 2017;18:42-55.
  12. Blumenfeld H. Neuroanatomy through clinical cases.
  13. Sheppard SM, Hillis AE. That's right! Language comprehension beyond the left hemisphere. Brain. 2018;141:3280-89.
  14. Winner E, Gardner H. The comprehension of metaphor in brain-damaged patients. Brain. 1977 ;100:717-29.
  15. McDonald S, Pearce S. Clinical insights into pragmatic theory: Frontal lobe deficits and sarcasm. Brain and language. 1996;53:81-104.
  16. Ackermann H, Riecker A. The contribution of the insula to motor aspects of speech production: a review and a hypothesis. Brain and language. 2004;89:320-28.
  17. Dogil G, Ackermann H, Grodd W, Haider H, Kamp H, Mayer J, Riecker A, Wildgruber D. The speaking brain: a tutorial introduction to fMRI experiments in the production of speech, prosody and syntax. Journal of Neurolinguistics. 2002;15:59-90.
  18. Kemeny S, Ye FQ, Birn R, Braun AR. Comparison of continuous overt speech fMRI using BOLD and arterial spin labeling. Human brain mapping. 2005;24:173-83.
  19. Larsen B, Skinhøj E, Lassen NA. Cortical activity of left and right hemisphere provoked by reading and visual naming. A rCBF study. Acta Neurologica Scandinavica. Supplementum. 1979:6-7.
  20. Joanette Y, Goulet P. Right hemisphere and verbal communication: Conceptual, methodological, and clinical issues. Clinical aphasiology. 1994;22:1-23.
  21. Lehman Blake M, Duffy J, Tompkins C, Myers P. Right hemisphere syndrome is in the eye of the beholder. Aphasiology. 2003;17423-32.
  22. Aphasia Lab. Q&A Bank. [Internet]. [Place unknown]: Aphasia Lab; [cited 2024 March 2]. Available from: https://aphasialab.org/qab/
  23. Wilson SM, Eriksson DK, Schneck SM, Lucanie JM. A quick aphasia battery for efficient, reliable, and multidimensional assessment of language function. PloS one. 2018;13:e0192773.
  24. Alexander MP, Annett M. Crossed aphasia and related anomalies of cerebral organization: case reports and a genetic hypothesis. Brain and language. 1996;55:213-39.
  25. Coppens P, Hungerford S, Yamaguchi S, Yamadori A. Crossed aphasia: an analysis of the symptoms, their frequency, and a comparison with left-hemisphere aphasia symptomatology. Brain and language. 2002;83:425-63.
  26. Pedersen PM, Stig Jørgensen H, Nakayama H, Raaschou HO, Olsen TS. Aphasia in acute stroke: incidence, determinants, and recovery. Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society. 1995;38:659-66.
  27. Gajardo-Vidal A, Lorca-Puls DL, Hope TM, Parker Jones O, Seghier ML, Prejawa S, Crinion JT, Leff AP, Green DW, Price CJ. How right hemisphere damage after stroke can impair speech comprehension. Brain. 2018;141:3389-404.
Zaidel E. Auditory vocabulary of the right hemisphere following brain bisection or 

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