fakhir, T., Farhan, R., Fayadh, N., Al-Saadi, W. (2025). Hyperdence Middle Cerebral Artery :Quantification of CT Density in Strocke and Non-Strocke Patients. , 24(2), 266-272. doi: 10.52573/ipmj.2025.149534
tariq salman fakhir; Rana mansoor Farhan; Noor Abbas Hummadi Fayadh; wasan Ismail Al-Saadi. "Hyperdence Middle Cerebral Artery :Quantification of CT Density in Strocke and Non-Strocke Patients". , 24, 2, 2025, 266-272. doi: 10.52573/ipmj.2025.149534
fakhir, T., Farhan, R., Fayadh, N., Al-Saadi, W. (2025). 'Hyperdence Middle Cerebral Artery :Quantification of CT Density in Strocke and Non-Strocke Patients', , 24(2), pp. 266-272. doi: 10.52573/ipmj.2025.149534
fakhir, T., Farhan, R., Fayadh, N., Al-Saadi, W. Hyperdence Middle Cerebral Artery :Quantification of CT Density in Strocke and Non-Strocke Patients. , 2025; 24(2): 266-272. doi: 10.52573/ipmj.2025.149534

Hyperdence Middle Cerebral Artery :Quantification of CT Density in Strocke and Non-Strocke Patients

Iraqi Postgraduate Medical Journal
Article 17, Volume 24, Issue 2, April 2025, Pages 266-272    PDF (364.02 K)
Document Type: Research Paper
DOI: 10.52573/ipmj.2025.149534
Authors
tariq salman fakhir* 1; Rana mansoor Farhan2; Noor Abbas Hummadi Fayadh3; wasan Ismail Al-Saadi4
1Radiology institute
2medical city Radiology Institute
3CABAHS-Rad Lecturer Al-Naharaincollege of medicine senior radiologist Alimamain AlKadhimain medical city
4Al-Nahrain College of Medicine Al-Nahrain University, Kadhimiya, Baghdad, Iraq
Abstract
AbstracBackgrounThe hyperdense middle cerebral artery sign refers to an appearance of increase attenuation of the proximal (MCA) that is often associated with thrombosis of the M1 MCA segment and may be the only diagnostic feature on computed tomography early after ischemic stroke.To evaluate the CT density number of hyperdense MCA presented with hyperacute and acute stroke and comparing the measurements with those of non-stroke patients with hyperdense MCA on the baseline non-enhanced brain CT. MethodsThis study is comparison cross sectional study included two groups; group A: patients aged ≥35 years with clinical diagnosis of hyperacute (first 6 hours) or acute (6 hours-4 days) stroke who were referred to the CT unit and group (B) patients aged ≥35 years referred to the CT unit for various indication with no clinical evidence of stroke who were labeled by two radiologists as normal brain CT. ResultsThis study showed there is a statistically significant difference between the mean density of the dense MCA at the site of stroke (48 HU) when compared tothecontralateral MCA (39.7 HU) with average difference in density value of 8.3 HU (p<0.001), the same applies when tested against the dense MCAS in the non-stroke group (42.2 HU) with average difference of 5.8 HU (p<0.002). However, no significant difference was found when testing the density in the non-stroke group against that of the contralateral MCAS in stroke group (p=0.2). Moreover, significant variation was observed between the density ratio of stroke and non-stroke patients (1.29 vs 1.02, p=0.009). A cutoff MCA density of 41.7 HU was proposed to the predict pathological state.ConclusionHyperdense MCA is associated with acute ischemic stroke exhibit higher CT attenuation value that of contralateral normal vessel or dense MCAS in healthy individuals. A CT density value of >41.7 HU is suggested as the best limit to mark the distinction.
Keywords
Hyperdense middle cerebral artery; stroke; CT density
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