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Influence of Age and Body Mass Index on Spirometry Parameters in Women with Hypothyroidism | ||
| Annals of the College of Medicine, Mosul | ||
| Volume 47, Issue 1, June 2025, Pages 41-46 PDF (642.79 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/mmed.2025.155613.1295 | ||
| Authors | ||
| Dalal Ayad Al-Alaf* ; Afraa Mohammed Alameen; Janan Abdalrazzak Alrefaee | ||
| College of Medicine, University of Mosul, Mosul, Iraq | ||
| Abstract | ||
| Background: Thyroid hormones are essential for the function of the respiratory system. Hypothyroidism affects respiration by a decrease in lung compliance, muscle weakness, and a reduction in ventilatory drive. Lung function is influenced by age and body mass index, but the correlation of spirometry with BMI and age in hypothyroid women remains poorly understood. Aims: To investigate the effect of age and BMI on spirometry parameters in hypothyroid women in Nineveh Governorate. Materials and Methods: A case-control study of 50 newly diagnosed hypothyroidism and 50 euthyroid individuals. Measurement of spirometry parameters such as FVC, FEV1, and FEV1/FVC with a spirometer. Weight and height were measured to calculate BMI. Results: A significant negative correlation between age and FVC% was predicted in the hypothyroid group (r = -0.364, p = 0.009). Nevertheless, FEV1/FVC exhibited a significant negative correlation with BMI in the hypothyroid group (r = -0.296, p = 0.037). Conclusion: Lung function declines with age in women with hypothyroidism, especially FVC% predicted. BMI appears to increase the airflow limitation as pronounced by a decrease in FEV1/FVC in hypothyroid women. | ||
| Keywords | ||
| Hypothyroidism; Body mass Index (BMI); Spirometry | ||
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