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Evaluation of the Effectiveness of Chlorhexidine Gluconate Gel on Periodontal Parameters and Fusobacterium Nucleatum Pathogen in Periodontitis Patients | ||
| Tikrit Journal for Dental Sciences | ||
| Volume 13, Issue 1, June 2025, Pages 109-118 PDF (387.8 K) | ||
| DOI: 10.25130/tjds.13.1.12 | ||
| Authors | ||
| Mohand Falah Abdullah* ; Alaa Omran | ||
| College of Dentistry, University of Baghdad, Baghdad, Iraq. | ||
| Abstract | ||
| Background: Periodontal disease, a prevalent oral disease affecting 10-15% of adults globally, leads to tissue damage and bone loss. Fusobacterium nucleatum, a bacterium from the Bacteroidaceae family, significantly contributes to this disease. Chlorhexidine, a powerful antibacterial agent. It is believed to be the gold-standard for conventional periodontal treatment due to its effectiveness in eliminating periodontal pathogenic bacteria. Aim of study: Estimate the effictiveness of chlorhexidine gluconate gel in the nonsurgical management of periodontitis patients. Methods: by employing single-blinded, split-mouth randomized clinical trial. It included ten attending patients diagnosed with generalized unstable periodontitis. A split-mouth design was used,and 15 test and 15 control sites were selected. every subject had two locates selected: a control locate that received subgingival debridement with placebo gel and an experiment locate that received subgingival debridement with chlorhexidine gel. Clinical parameters Levels were measured for full dentition. Results: Bleeding on probing sites significantly decreased after treatment in the CHX group. Pocket probing depths, clinical attachment levels, also bacteria found to be significantly reduced after treatment in both groups. A statistically significant strong positive correlation has been identified regarding bacteria and periodontal probing depth, and a positive correlation has been identified regarding bacteria and clinical attachment level. Conclusion: Treatment with chlorhexidine gluconate gel can lower Fubacterium nucleatum bacterial count in periodontal pockets and significantly decrease bleeding on probing and clinical attachment scores within the locates treated with chlorhexidine gluconate. | ||
| Keywords | ||
| chlorhexidine clinical trial fusobacterium nucleatum gel. periodontitis | ||
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