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Histological Evaluation of Local Application of Cress Seeds Oil on Wound Healing in Facial Skin Rat | ||
| Tikrit Journal for Dental Sciences | ||
| Volume 13, Issue 1, June 2025, Pages 141-152 PDF (1.27 M) | ||
| DOI: 10.25130/tjds.13.1.15 | ||
| Authors | ||
| Khalid Abdulridha Al-abedi1; Enas F. F. Kadhim* 2 | ||
| 1Department of Oral Diagnosis (Oral histology),Dentistry University of Baghdad,Baghdad, Iraq | ||
| 2Department of Oral Diagnosis, College of Dentistry, University of Baghdad | ||
| Abstract | ||
| Background: The process of skin healing necessitates the restoration of the body's structural integrity. This physiological process includes the extracellular matrix, blood cells, cytokines,and growth factors. Cress seed oil is a widely utilized herbal remedy that is believed to have medicinal activities as an antioxidant, antimicrobial, and anti-inflammatory. Objective: Assess the influence of applying cress seeds oil directly to facial cutaneous wounds in rats to determine its effect on healing. Materials and Methods: Sixty male Albino rats, with an average weight 200 -300 g were studied. Full thickness surgical incisional wounds were made in the cutaneous surface of each rat's cheek.The rats have been divided into the subsequent groups using random assignment: Control group: (n=30), where wounds were allowed to heal without any intervention. Experimental group:(n=30), wounds were treated daily with topical application of cress seed oil. Assessment of wound contraction, epithelial thickness, inflammatory cells and blood vessels quantification.The animals had scarification at the healing periods (days three & seven). Results: There is a noticeable rise in wound contraction and epithelial thickness over time with a significant difference observed in the experimental group at day 7. The number of inflammatory cells reduced over time. The experimental group exhibited the highest mean values for blood vessel count on day 7. Conclusion: The results of the present study demonstrate that the use of cress seeds oil applied directly to the skin wounds of rats enhances the healing process. | ||
| Keywords | ||
| albino rats angiogenesis Antiinflammatory. Cress seeds oil Skin Wound Healing | ||
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