- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Histological Evaluation of the Effect of Squalane Oil /Rosehip Oil on Facial Wound Healing of Rat | ||
| Tikrit Journal for Dental Sciences | ||
| Volume 13, Issue 1, June 2025, Pages 153-167 PDF (1.08 M) | ||
| DOI: 10.25130/tjds.13.1.16 | ||
| Authors | ||
| Jwan Arkan Mohammed Saeed1; Enas Fadhil Kadhim* 2 | ||
| 1Department of Oral Diagnosis (Oral histology), Dentistry, University of Baghdad, Baghdad, Iraq | ||
| 2Department of Oral Histology and Biology, Dentistry, University of Baghdad, Baghdad, Iraq | ||
| Abstract | ||
| Background: Wound healing is achieved by 3 processes: hemostasis, inflammation, proliferation, and remodeling. squalene is considered a natural product with some ability to influence the immunomodulation of macrophages where it could help the “last stage remodeling and wound closure” because of its anti-inflammatory properties. Rosehip oil can shorten epithelialization time while decreasing the number of inflammatory cells that invade. Objective: Study the efficacy of squalene oil and rosehip oil separately or as a combination in the healing of facial skin wounds of rats histologically. Patients and Methods: forty-two rats were subjected to facial skin wounds. They separated the animals into: A. The control group on the left side left for spontaneous healing without any treatment. B. Experimental group on the right side which were divided to three groups for each oil and their combination. Then the specimens were taken on the 3rd and 7th day after wounding and prepared for histological examination (H&E stain). Results: The greatest wound contraction was found in the squalane oil group on the 7th day. The histological evaluation showed that the control group had the greatest inflammatory cell count on day 3. Regarding the epithelial thickness it was found is where the combination group had the highest levels of epithelial thickness compared to the squalane oil and rosehip oil groups. As for blood vessel count, it was found that the greatest blood vessel counts in the rosehip oil group. Conclusion: results showed that the use of squalane oil and rosehip oil separately or as a combination can be beneficial for wound healing. | ||
| Keywords | ||
| rosehip oil squalane oil wound healing | ||
|
Statistics Article View: 769 PDF Download: 205 |
||