- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
The Association of Periodontitis and different BMI categories with Serum Chemerin Levels -: An Observational Case-Control Study | ||
| Tikrit Journal for Dental Sciences | ||
| Volume 12, Issue 2, December 2024, Pages 441-451 PDF (381.6 K) | ||
| DOI: 10.25130/tjds.12.2.20 | ||
| Authors | ||
| Ghufran Ibrahem Mohammed* ; Alaa Omran Ali | ||
| Department of Periodontics, College of Dentistry, University of Baghdad Iraq | ||
| Abstract | ||
| Background: Chemerin is a adipocytes, epithelial cells, endothelium, fibroblasts, and keratinocytes - derived chemotactic protein. This research was focused on possible connections between glycerin in serum, different body mass indexes (BMI), and appearance of the periodic disease. It is speculated that the findings of our work will help to deepen our comprehension of the interplay of adipokines, obesity, and periodontitis. Objective: The purpose of this endeavor is to establish the connections between serum chemerin, the value of BMI, and periodontitis to investigate the association between the indexes associated with the increase in obesity and the onset or aggravation of this disease. Methods: A total of 118 individuals volunteered to be a part of this research. serum obtained before the clinical investigations was the serum sample taken. participants were distributed into six groups: First group (C): 30 subjects with a normal BMI (18.5-24.9 kg/m^2) and a healthy periodontium; second group (Ov): 30 subjects with an overweight BMI (25–29.9 kg/m^2) and a healthy periodontium; third group (Ob): 30 subjects with an obesity BMI (≥ 30) and a healthy periodontium; fourth group (P): 30 periodontitis patients with a normal BMI (18.5-24.9 kg/m^2); fifth group (P+Ov): 30 periodontitis patients with an overweight BMI (25–29.9 kg/m^2) and sixth group (P+Ob): 30 periodontitis patients with obesity BMI (≥ 30). Evaluation of probe debut (PPD), clinical attachment loss (CAL), and bleeding upon probing (BOP) were the methods used in the periodontal test. Results: The findings of the study point out periodontal patients, and in particular, higher body mass index-filled serum levels of chemerin. Among all the study groups, patients with combined very severe obesity and periodontitis (P+Ob) were found to have the highest chemerin levels in their serum. Chemerin (C) of the control group with a weight within the normal range and a healthy area of periodontium was lower in reach. Conclusions: The results suggested that chemerin might be a good indicator biomolecule, which would provide information about the disease progress and deterioration, not only in the cases of overweight subjects but most probably in every person affected. may have a healing effect as its inflammatory effect could be counteracted. | ||
| Keywords | ||
| BMI Chemerin Inflammation Periodontitis S | ||
|
Statistics Article View: 350 PDF Download: 136 |
||