Serum and Salivary Ferritin Level in Relation to Iron Deficiency Patient with Recurrent Aphthous Stomatitis

Al-Hamdani, Ghaith Majid; Yas, Layla Sabri

doi:10.25130/tjds.11.2.16

	Serum and Salivary Ferritin Level in Relation to Iron Deficiency Patient with Recurrent Aphthous Stomatitis
Tikrit Journal for Dental Sciences
Volume 11, Issue 2, December 2023, Pages 304-309 PDF (230.01 K)
DOI: 10.25130/tjds.11.2.16
Authors
Ghaith Majid Al-Hamdani^* ¹; Layla Sabri Yas²
¹Department of Oral Medicine, College of Dentistry, University of Baghdad, Iraq
²Department of Oral Pathology, College of Dentistry, University of Baghdad, Iraq.
Abstract
Background: Recurrent aphthous stomatitis (RAS) is one of the most widespread disorders affecting the oral mucosa, with a prevalence of 50–66%. This study investigated the serum and salivary levels of ferritin between participants with recurrent aphthous ulcers and healthy. Methods: A total of 75 individuals participated in the research separated into three groups, clinically healthy control group (n=25), iron deficiency anemic patient with recurrent aphthous stomatitis (n=25), and iron deficiency anemic patient without recurrent aphthous stomatitis (n=25). The enzyme-linked immunosorbent assay measured the serum and salivary ferritin levels. Result: the serum and salivary levels of ferritin were significantly lower (p<0.05) in anemic groups compared to healthy controls.in the salivary ferritin, there was a statistically significant difference between anemic patients without aphthous ulcer and anemic with aphthous ulcer (p=0.015), while in the serum ferritin, there was non-significant difference. Conclusion: The severity of ferritin deficiency paly as a cofactor for the development and recurrence of recurrent aphthous stomatitis.
Keywords
Ferritin Recurrent aphthous stomatitis ELIS

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