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Isolation and Identification of Candida Species Causing Vulvovaginal Candidiasis from Patients with Vulvovaginitis Using the VITEK 2 System in Duhok City/Iraq. | ||
| Rafidain Journal of Science | ||
| Articles in Press, Accepted Manuscript, Available Online from 02 August 2025 | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/rjs.2025.159767.1451 | ||
| Authors | ||
| Sundis Abdulazeez Ahmed* ; Asia Abdulhameed Mohamed saadullah | ||
| Department of Biology, College of Science, University of Duhok, Kurdistan Region/ Iraq | ||
| Abstract | ||
| Vulvovaginal candidiasis (VVC) is a prevalent gynecological disease characterized by vaginal wall inflammation that is caused by Candida species. VVC impacts almost three-quarters of all women throughout their reproductive years. This study was aimed to assess the incidence and species distribution of Candida in Duhok women presenting with vaginal Candidiasis. Using selective media Sabouraud dextrose agar (SDA), germ tube test (GTT), chlamydospore formation, and CHROMagar. A total of 200 samples of high vaginal were collected from patients in Azadi teaching hospital. A total of 71 samples Candida species, 114 with normal flora, 14 with bacterial infection, and 1 with parasite infection. These isolates were subjected to GTT, chlamydospore formation, and inoculation on CHROMagar. Candida albicans was the main species isolated, followed by Candida glabrata, Candida krusei, and Candida tropicalis based on colony color. Following this, species confirmation and antifungal susceptibility testing are performed using the VITEK 2 system. Regarding antifungal sensitivity, micafungin and voriconazole have proven to be the most effective, exhibiting the lowest MIC values. These are followed by caspofungin, fluconazole, amphotericin B, and flucytosine, indicating their relative efficacy in treating Candida infections. This comprehensive approach ensures accurate identification and optimal treatment strategies for Candida species. | ||
| Keywords | ||
| Vaginal Candidiasis; Germ tube; Chlamydospores formation; CHROMagar; Vitek 2 system | ||
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