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Effect of Organic Acids and Probiotics on Methicillin-resistant and Vancomycin-resistant Staphylococcus aureus Isolation from Patients in the Dhi Qar Governorate | ||
| Rafidain Journal of Science | ||
| Articles in Press, Accepted Manuscript, Available Online from 05 August 2025 | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/rjs.2025.159886.1455 | ||
| Author | ||
| Riyadh Makttoof Jasim* | ||
| University of Mosul Collage of Science | ||
| Abstract | ||
| We highlight the prevalence of these strains in Dhi Qar Governorate and how to use alternative treatments based on available, inexpensive,and safe materials for human use.The goal of this study was to find out how well some organic acids and probiotics kill clinical isolates of MRSA and VRSA a big health problem.We obtained and processed 10patient samples using traditional microbiological procedures, followed by molecular testing for validation. We treated the isolates with four types of organic acids: acetic, lactic, citric, and oxalic acids. We also used locally isolated probiotics from sheep milk, sheep whey and cow whey,we also used a commercially available probiotic powder formulation consisting of three probiotic bacteria.Results demonstrated that organic acids showed much more antibacterial efficacy than the probiotic therapy.Acetic acid had the most efficiency among the acids, successfully suppressing bacterial growth at reduced doses. Lactic acid had the next highest efficacy, followed by citric acid with moderate activity,and oxalic acid exhibited the lowest effectiveness. The probiotic formulation decreased bacterial numbers to a degree, although its effect was far less marked than that of the organic acids.Based on these findings, organic acids, especially acetic acid, may work well as alternatives to or in addition to common antimicrobials.More research on how these drugs work and what they could be used for is needed to improve treatment options for resistant infections and patient outcomes in affected groups.The numbers indicate that updating current infection control methods to incorporate strategies based on organic acids is necessary to effectively combat resistant bacteria. | ||
| Keywords | ||
| Staphylococcus aureaus; Antibiotics; Organic acid; Probiotics | ||
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