Hatim, R., Younus, Z., Qazzaz, M., Hijazeen, R. (2025). Zingiber officinale (Ginger): A Comprehensive Review of Its Therapeutic Potential. , 22(4), 193-202. doi: 10.33899/iraqij.p.2025.163039.1163
Reyam Oday Hatim; Zaid Muwafaq Younus; Mohannad Emad Qazzaz; Rima Atallah Hijazeen. "Zingiber officinale (Ginger): A Comprehensive Review of Its Therapeutic Potential". , 22, 4, 2025, 193-202. doi: 10.33899/iraqij.p.2025.163039.1163
Hatim, R., Younus, Z., Qazzaz, M., Hijazeen, R. (2025). 'Zingiber officinale (Ginger): A Comprehensive Review of Its Therapeutic Potential', , 22(4), pp. 193-202. doi: 10.33899/iraqij.p.2025.163039.1163
Hatim, R., Younus, Z., Qazzaz, M., Hijazeen, R. Zingiber officinale (Ginger): A Comprehensive Review of Its Therapeutic Potential. , 2025; 22(4): 193-202. doi: 10.33899/iraqij.p.2025.163039.1163

Zingiber officinale (Ginger): A Comprehensive Review of Its Therapeutic Potential

Iraqi Journal of Pharmacy
Article 4, Volume 22, Issue 4, December 2025, Pages 193-202    PDF (785.67 K)
Document Type: Review Paper
DOI: 10.33899/iraqij.p.2025.163039.1163
Authors
Reyam Oday Hatim1; Zaid Muwafaq Younus* 1; Mohannad Emad Qazzaz1; Rima Atallah Hijazeen2
1Department of Pharmacognosy and Medicinal Plants, College of Pharmacy, University of Mosul, Mosul, Iraq.
2Department of Biopharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, University of Jordan, Amman 11942 Jordan.
Abstract
Background: Officially called (Zingiber officinale Roscoe), which is ginger, is a commonly used spice that is easily accessible. As a ginger spice, it contains various chemical constituents, including phenolic compounds, terpenes, polysaccharides, lipids, organic acids, and raw fibers.  Aim: In this review, we describe the latest data on ginger’s bioactive constituents, which incorporate ginger biochemicals and ginger bioactivities and their actions. The review will also discuss certain therapeutic applications of ginger in light of the current available literature. Methods: The reviewed data were abstracted utilizing scientific platforms, including Web of Science, Scopus, and Google Scholar. Results: The health benefits of ginger are primarily attributed to the phenolic compounds gingerols and shogaols. Ginger exhibits multiple biological activities, including antioxidant, anti-inflammatory, antimicrobial, anticancer, neuroprotective, and cardiovascular protective properties. Additionally, ginger has respiratory protective, anti-obesity, antidiabetic, as well as anti-nausea and antiemetic effects. Conclusion: According to this review, ginger has a great bioactive profile, and its active components have positive therapeutic effects.

Highlights
  • Zingiber officinale contains variable bioactive components, mostly phenolic and terpene constituents.
  • Constituents of Ginger have recognized anti-inflammatory, antioxidant, and antimicrobial activities.
  • The actions of Ginger content refer to a promising therapeutic aid in conditions such as Diabetes Mellitus and cardiovascular diseases.
Keywords
Zingiber; Inflammatory; Bioactive; Antioxidant; Antimicrobial
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