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Evaluation of the Antifungal Effects of Phenolic Compounds and Volatile Oils Extracted from Petroselinum sativum L. on Microsporum canis and Trichophyton mentagrophytes | ||
| Al-Zahraa Journal for Health and Medical Sciences | ||
| Article 4, Volume 3, Issue 3, September 2025, Pages 54-63 PDF (868.97 K) | ||
| Document Type: Research Article | ||
| Author | ||
| Nadia N.H. AL masaoodi* | ||
| 1College of Medical and Health Technologies, Al-Zahraa University for Women, Kerbala, Iraq 2College of Education for Pure Sciences, University of Kerbala, Iraq | ||
| Abstract | ||
| A current study on the volatile oil and phenolic extract of Petroselinum sativum L. was conducted to evaluate the antifungal activity of the plant against Trichophyton mentagrophytes and Microsporum canis, the phytochemical constituents were first examined by preparing an ether-alcoholic extract of the leaves. The antifungal activity of the phenolic extract and volatile oil was evaluated against fungi at different concentrations. At the lowest tested concentration 0.5 mg/mL, the volatile oil produced inhibition zones of 2.23 mm against M. canis and 1.12 mm against T. mentagrophytes . The phenolic extract showed stronger inhibitory effects. At 1 mg/mL, inhibition were 3.78 mm for M. canis and 1.99 mm for T. mentagrophytes. At 3 mg/mL resulted in inhibition were of 4.78 mm for M. canis and 6.56 mm for T. mentagrophytes, while at 8 mg/mL with the same values, suggesting a possible plateau effect at this level. The inhibition area of phenol was 2.12 mm against Trichophyton mentagrophytes, 3.78 mm against Microsporum canis at 3 mg/mL .At 5 mg/mL, inhibition zones reached 4.98 mm for M. canis and 2.98 mm for T. mentagrophytes. The highest activities were observed at 10 and 12 mg/mL. At 10 mg/mL, inhibition zones measured 6.12 mm for M. canis and 5.34 mm for T. mentagrophytes, while at 12 mg/mL the inhibition zones increased further to 7.34 mm and 5.99 mm, respectively. | ||
| Keywords | ||
| Petroselinum sativum; volatile oil; antifungal; Trichophyton mentagrophytes; Microsporum canis | ||
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