Association of C-Reactive Protein Levels with the Severity of Spontaneous Intracerebral Hemorrhage

Shaker, Omar Mahmoud; Al-Hamadani, Hasan Aziz

doi:10.52573/ipmj.2025.157167

	Association of C-Reactive Protein Levels with the Severity of Spontaneous Intracerebral Hemorrhage
Iraqi Postgraduate Medical Journal
Article 13, Volume 25, Issue 1, January 2026, Pages 87-93 PDF (924.39 K)
Document Type: Research Paper
DOI: 10.52573/ipmj.2025.157167
Authors
Omar Mahmoud Shaker^* ¹; Hasan Aziz Al-Hamadani²
¹Diyala Director of health
²College of Medicine. Al-Nahrain University.
Abstract
ABSTRACT: BACKGROUND: Intracerebral hemorrhage (ICH) is a critical and debilitating form of stroke, affecting over one million people globally each year. Recent research has focused on exploring the role of C-reactive protein (CRP) in ICH cases. OBJECTIVE: This study aimed to investigate the association between CRP levels and the severity of spontaneous ICH. PATIENTS AND METHODS: A cross-sectional study was conducted at Al-Imamein Al-Kadhimein Medical City and Al-Yarmouk Teaching Hospital. It included patients aged 18 years or older with a primary diagnosis of ICH within 48 hours of symptom onset. RESULTS: A total of 107 patients with acute ICH were included. The majority (57%) were aged 46–65 years, with a mean age of 58.65 years. Males accounted for 66.4% of cases. Elevated CRP levels (>10 mg/L) were observed in 63.6% of patients, with a mean CRP of 37.32 mg/L. The average ICH score was 1.14, and most cases (37.4%) had an ICH score of 1. A Glasgow Coma Scale (GCS) range of 13–15 was most common, with a mean GCS of 12.95. CONCLUSION: CRP levels in ICH patients were not significantly correlated with GCS, ICH scores, or mortality risk, suggesting a limited role in acute severity.
Keywords
KEYWORDS: CRP; intracerebral hemorrhage; severity

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