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Assessing the Effects of Age, Sex, and Body Mass Index on Glycemic and Lipid Levels in Newly Diagnosed Type 2 Diabetic Patients: A Cross-Sectional Study | ||
| Al-Kunooze Scientific Journal | ||
| Volume 11, Issue 4, October 2025, Pages 99-114 PDF (559.23 K) | ||
| Document Type: Original Article | ||
| Author | ||
| Abdullah Abbas Hamza Al-Rubaie, Ahmed Abdul-Hussein Mohsen , Walaa Ismail Jasim | ||
| Abstract | ||
| Newly diagnosed type 2 diabetic patients show varied metabolic profiles influenced by factors like age, sex, and body mass index, which affect disease progression and risk of other health problems. To evaluate how demographic factors such as age, sex, and body mass index (BMI) influence glycemic control and lipid profile parameters in patients newly diagnosed with type 2 diabetes mellitus. The study included 60 newly diagnosed type 2 diabetic patients aged 30 to 75 years. Blood samples were collected after overnight fasting; they were divided into two parts, with the EDTA tube used immediately for HbA1c measurement, while the other parts were separated to obtain serum for biochemical parameters. Biochemical measurements included glucose and lipid profile by enzymatic methods, HbA1c by ion exchange HPLC, and insulin by sandwich electrochemiluminescence immunoassay. Insulin resistance was calculated using the HOMA-IR formula. Biochemical parameters were not varied significantly by age or sex except for higher total cholesterol and HDL cholesterol in females. Obesity was strongly associated with increased insulin resistance and an adverse lipid profile characterized by elevated TG, VLDL cholesterol, LDL cholesterol, and reduced HDL cholesterol. Glycemic control markers (glucose, HbA1c) were not significantly linked to lipid abnormalities. This study concluded that age and sex do not affect glycemic control and lipid profile, except that women have higher total cholesterol and HDL cholesterol. However, obesity is strongly associated with increased insulin resistance and an adverse lipid profile. | ||
| Keywords | ||
| type 2 diabetes mellitus; insulin resistance; glucose; obesity; lipid | ||
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