Assessment the Effect of 1% Hyaluronic Acid and 0.2% chlorhexidine on the Healing of Soft Tissue after Tooth Extraction (Clinical Comparative Study)

Mahmood, Ahmed Abdulkareem; Qais, Sohaib; Amer, Ahmed; Mizher, Saber

doi:10.25130/tjds.2025.190432

	Assessment the Effect of 1% Hyaluronic Acid and 0.2% chlorhexidine on the Healing of Soft Tissue after Tooth Extraction (Clinical Comparative Study)
Tikrit Journal for Dental Sciences
Volume 13, Issue 2, December 2025, Pages 352-361 PDF (716.91 K)
DOI: 10.25130/tjds.2025.190432
Authors
Ahmed Abdulkareem Mahmood^* ¹; Sohaib Qais²; Ahmed Amer¹; Saber Mizher¹
¹Department of Oral and Maxillofacial Surgery, Dentistry, University of Tikrit, Iraq.
²Department of Pediatric Dentistry, Dentistry, University of Tikrit, Iraq.
Abstract
Background: The most frequent procedure a dentist performs is dental extraction, which involves removing the diseased tooth without harming the surrounding tissue to promote the best possible healing. Aims: The goal of the current study was to estimate the impact of local application of hyaluronic acid gel treatment on soft tissue healing following mandibular molar extraction. Patients and Methods: This study was conducted in the Department of Oral and Maxillofacial Surgery at the University of Tikrit's Faculty of Dentistry; the trial was conducted from February to May 2023. The research included a total of 30 healthy patients with asymptomatic teeth at the time of extraction (nineteen male and eleven female) between the ages of 18 and 35 were included in the study. Patients were split into two groups at random; Group one received an extraction site treatment of Perio KIN Hyaluronic 1%® gel (1% hyaluronic acid and 0.2% chlorhexidine) while Group two (control group) received no treatment. A numerical periodontal probe was used to grade the patients at the first and seventh postoperative days. Results: Buccolingual width were maximum on the first postoperative day and then progressively declined in the seventh postoperative day for both the Control and hyaluronic acid groups. On the seven postoperative days, the buccolingual widths of the Control and hyaluronic acid groups differed significant statistically. Conclusions: The study's findings demonstrated that hyaluronic acid accelerated soft tissue healing subsequent tooth extraction.
Keywords
Tooth Extraction; Mandibular Molars; Hyaluronic acid; Soft Tissue Healing

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