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Evaluation of the antifungal effects of Mentha piperita L. and Ocimum basilicum L. extracts on the antifungal ,lung and colon cancer cells | ||
| Al-Zahraa Journal for Health and Medical Sciences | ||
| Volume 3, Issue 4, December 2025, Pages 23-33 PDF (1 M) | ||
| Document Type: Research Article | ||
| Author | ||
| Nadia N.H. AL masaoodi* | ||
| 1College of Medical and Health Technologies, Al-Zahraa University for Women, Kerbala, Iraq 2College of Education for Pure Sciences, University of Kerbala, Iraq | ||
| Abstract | ||
| The therapeutic properties of Mentha piperita and Ocimum basilicum are the subject of a current experimental investigation. The isolated population was stimulated and cultivated on SDA medium, and the fungal organisms utilized in the study were acquired from the College of Science, University of Karbala laboratory. Mint then Ocimum basilicum were extracted from those plants, which were taken from the botanical garden, thoroughly cleaned, and dried in the open before being processed into a fine powder using a grinder. Following treatment with peppermint and Ocimum basilicum, the viability of a lung cancer cell line was assessed using the MTT assay on a Soxhlet device. Using a 25%concentration, the results demonstrated the effect of the plant extracts on the development of the common skin disease Trichophyton rubrum. The results indicated statistically significant differences between the two extracts at this concentration, showing a marked increase in inhibition of 47.84%for peppermint and 49.63% for Ocimum basilicum, with a p-value of 0.0061. At the 25% concentration, both Ocimum basilicum and Mentha piperita extracts showed an effect on A549 cancer cells, with peppermint inhibiting 43% and basil inhibiting 37%. The consequences of preparations of Ocimum basilicum and peppermint Mentha piperita on colon cancer cells are shown. The Mentha piperita extract had a 38% percent inhibitory impact when given at a 25% percent dosage, whereas the Ocimum basilicum extract demonstrated a 44% percent inhibiting impact. | ||
| Keywords | ||
| colon cancer; lung cancer; Mentha piperita; Ocimum basilicum; Trichophyton rubrum | ||
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