Synthesis and Characterization of Co+2,Ni+2,Cu+2 and Cd+2 Complexes with (4-(tert-butyl) phenyl) thio) Alkane Ligands

Tariq, Farah

doi:10.33899/rjs.2025.165229.1512

	Synthesis and Characterization of Co+2,Ni+2,Cu+2 and Cd+2 Complexes with (4-(tert-butyl) phenyl) thio) Alkane Ligands
Rafidain Journal of Science
Articles in Press, Accepted Manuscript, Available Online from 21 December 2025
Document Type: Research Paper
DOI: 10.33899/rjs.2025.165229.1512
Author
Farah Tariq^*
Dept. of Chem., College of Science, Mosul University
Abstract
A series of new complexes of the type [M(Ln)Cl2], , where L= L1 , L2 , L3, L1= 1,2-bis((4-(tert-butyl)phenyl)thio)ethane,L2=1,3-bis((4-(tert-butyl)phenyl)thio) propane, L3 = 1,4-bis((4-(tert-butyl)phenyl)thio) butane, M=Co+2, Ni+2 , Cu+2 and Cd+2 were prepared and characterized by molar conductance, IR, UV/Vis spectral studies, magnetic measurements and metal content analysis. Magnetic moment and electronic spectra indicate that all of the complexes show a tetrahedral geometry . Both 1,2-bis((4-(tert-butyl)phenyl)thio)ethane (L1), 1,3-bis((4-(tert-butyl)phenyl) thio) propane (L2), and 1,4-bis((4-(tert-butyl)phenyl)thio)butane (L3), along with their Co(II), Ni(II), Cu(II), and Cd(II) coordination complexes, were synthesized and thoroughly physicochemically characterized. Tetrahedral geometries and bidentate sulfur coordination were validated by spectroscopic, magnetic, and conductivity data. The complexity was improved. When the ligands' antimicrobial potential was systematically evaluated against representative bacterial strains, complex (1) demonstrated the greatest inhibition against Escherichia coli (27 mm) and Staphylococcus aureus (29 mm). These findings demonstrate the potential of metal complexes based on thioethers for use in bioinorganic and medicinal chemistry in the future.
Keywords
Alkane; Ligands; Complexes; Metals; synthesis

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