A review on the Production, Utilization, and Biological Activity of Benzimidazole Derivatives

Taresh, Ban Hasan; Taresh, Ban Hasan

	A review on the Production, Utilization, and Biological Activity of Benzimidazole Derivatives
Al-Zahraa Journal for Health and Medical Sciences
Volume 3, Issue 4, December 2025, Pages 85-101 PDF (987.82 K)
Document Type: Review Article
Authors
Ban Hasan Taresh^* ¹; Ban Hasan Taresh²
¹Kerbala University / College of Science / Chemistry Department
²Chemistry Department, Science College, Kerbala University, Iraq, Karbala
Abstract
Benzimidazole is an aromatic heterocyclic chemical molecule that is white and solid. It is created when the heterocyclic imidazole aromatic ring and the aromatic benzene ring fuse. Its usual formula is C7H6N2, and it is also known as 1H-1, 3-benzimidazole and 1H-benzo[d]imidazole. The unique characteristics of the chemical molecules formed from the benzimidazole substance, along with its several significant therapeutic capabilities and well-known biological uses, have piqued researchers' interest in its study and use during the past few decades.Since benzimidazole resistance is common in many fungal populations, effective resistance management strategies must be put into place as soon as possible to postpone or stop additional changes in the target infections' sensitivity. For benzimidazoles, there are no particular guidelines. Alternations and mixes are both effective ways to reduce the likelihood that resistance may emerge. When using tank mixes, the benzimidazole fungicide must be sprayed at the recommended dosage in conjunction with the proper dosage of a partner fungicide that is both effective and non-cross-resistant.
Keywords
Benzimidazole; Synthesis; Reaction; Biological Activity

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