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The role of vitamin E In reducing the side effects of Gabapentin on some histological parameters related to the heart in male albino rats | ||
| Al-Qadisiyah Journal of Pure Science | ||
| Volume 30, Issue 2, December 2025, Pages 200-209 PDF (618.13 K) | ||
| DOI: 10.29350/qjps.2025.190631 | ||
| Abstract | ||
| The study was designed to evaluate the role of vitamin E in reducing the side effects of gabapentin on the heart in male albino rats,(30) males were used, who were divided into three equal groups : The control group was given physiological saline solution in concentration( 0.9% ), the treatment group T1 was given gabapentin at a concentration of (100mg / Kg) of body weight, treatment group (T2) was given gabapentin at a concentration of (100mg / Kg) of body weight and vitamin E at a concentration of 80 mg/kg of body weight,The results showed that the drug algapapentin caused tissue changes in the heart muscle, represented by atrophy of the cardiac muscle fibers, the appearance of spaces between them, and congestion in the blood vessels ,Vitamin E helped reduce them. | ||
| Keywords | ||
| Gabapentin; vitamin E; heart | ||
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