GC-Mass Spectrometry Based Metabolomic Profiling of Three Different Propolis Extracts

Hasan, Rosa Mohammed; Safah AL-ardhi, Duaa Namaa; Ghazi, Ali M.

doi:10.29079/qjvms.2025.155851.1053

	GC-Mass Spectrometry Based Metabolomic Profiling of Three Different Propolis Extracts
Al-Qadisiyah Journal of Veterinary Medicine Sciences
Volume 24, Issue 2, December 2025, Pages 9-15 PDF (542.2 K)
Document Type: Research Paper
DOI: 10.29079/qjvms.2025.155851.1053
Authors
Rosa Mohammed Hasan^* ¹; Duaa Namaa Safah AL-ardhi²; Ali M. Ghazi³
¹university of Al-Qadisiyiah/ College of vet. medicine
²College of Veterinary medicine, University of Al-Qadisiyah, Iraq.
³University of Al-Qadisiyah
Abstract
Propolis is a natural substance rich in medically active chemical compounds. The presence of these compounds depends on a variety of factors, including the method of extraction and the solvent used for the extraction process. The current work aimed to investigate the effect of extracting propolis using different solvents on its chemical composition. The propolis extraction ratio were 34.53, 43.4 and 38.68% for watery, ethanolic, and ethyl acetate propolis extract respectively. The chemical composition of three extracts was analyzed using GC-Mass analysis which identified 16, 26, and 24 chemical components in watery, ethanolic, and ethyl acetate extracts respectively. The chemical composition of three extracts was varied greatly but all extracts were rich in phenolic compounds. 5-hydroxy-7-methoxyflavanone and 2-isopropenyl dihydrofuran were predominant in the watery extract whereas 1-methylethyl)-8-oxo-1,2-dihydrofurano, Malonic acid, 6-heptynyl, and 1,4-Naphthalenedione, 2-1-buten were predominant in ethanolic extract. 2H-1-Benzopyran-2-one-7-methoxy, 9-Tetradecynoicacid, methyl ester, and 9-Octadecenoic acid were predominant in the ethyl acetate extract
Keywords
Key words: Propolis; Extraction; GS-Mass; Metabolomic

Statistics Article View: 154 PDF Download: 207