Frequency of Prediabetes and Diabetes among Women with Polycystic Ovary Syndrome in Basrah

Httaihet, Rehab . H.; Ajlan, Salman K; Al-Waeely, Faiz A

doi:10.33762/mjbu.2025.164064.1319

	Frequency of Prediabetes and Diabetes among Women with Polycystic Ovary Syndrome in Basrah
The Medical Journal of Basrah University
Article 14, Volume 43, Issue 2, December 2025
Document Type: Research Paper
DOI: 10.33762/mjbu.2025.164064.1319
Authors
Rehab . H. Httaihet^* ¹; Salman K Ajlan^* ²; Faiz A Al-Waeely^* ¹
¹University of Basrah/College of Medicine
²University of Basrah/College of Medicine,
Abstract
Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting reproductive-age women, often associated with metabolic disturbances such as insulin resistance (IR), prediabetes, and type 2 diabetes (T2D). Aims of the study: To determine the frequency of prediabetes and diabetes among women with PCOS in Basrah. Subjects and Methods: This is a case-control study that included 100 women diagnosed with PCOS according to Rotterdam criteria and 100 age-matched control women. Fasting plasma glucose (FPG) and glycated haemoglobin (HbA1c), testosterone, and lipid profile were measured. Prediabetes and diabetes were defined according to ADA criteria. Results: Among the PCOS group, 52% showed normoglycemia, 29% were prediabetic, while 19% were diabetic (P< 0.001). FPG (P< 0.001) and HbA1c (P< 0.01) levels were significantly higher among women with PCOS compared to controls. Conclusion: The frequency of prediabetes and diabetes is significantly higher among women with PCOS compared to control women. Thus, PCOS imposes a substantial risk for future development of T2D, and hence, cardiovascular disease risk. Early screening and metabolic monitoring among women with PCOS are crucial to prevent long-term adverse cardiovascular disease outcomes.
Keywords
PCOS; Prediabetes; Diabetes; Insulin Resistance

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