- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Gut Microbiome and Breast Cancer: A Concise Review | ||
| Al-Kunooze Scientific Journal | ||
| Volume 12, Issue 2, April 2026, Pages 184-200 | ||
| Document Type: Review | ||
| DOI: 10.36582/ksj.2026.168874.1021 | ||
| Authors | ||
| Yasameen Hameed Jasim* 1; Ashraq Monir Mahmed2; Rasha Hameed Jasim3; Mustafa Abd- almajeed Abd-alkareem3 | ||
| 1Samarra | ||
| 2Department of Food Science, College of Agricultural Engineering Sciences, University of Baghdad, Iraq | ||
| 3Department of pathological analysis disease. College of Applied Sciences, Samarra University, Samarra , Iraq | ||
| Abstract | ||
| The Gut Microbiome influences Breast Cancer risk through Estrogen Metabolism, inflammation throughout the body, and Immune System Regulation. A decrease in the diversity of microbes will result in an imbalance of the gut microbiome (dysbiosis), which will support the increase of pro-inflammatory microbes, leading to elevated Circulating Estrogens and ultimately supporting greater Tumor Growth; conversely, some beneficial microbes (such as Lactobacillus) will help maintain hormonal equilibrium, reducing the likelihood of developing breast cancer. The combination of what we eat and how we eat (diet) has a significant impact on the types of bacteria that grow and multiply within our gut microbiome. Studies show that a diet rich in Fiber and Plant-Based foods supports the growth of short-chain fatty acids. SCFAs(bacteria, while diets that are high in Fat and Sugar contribute to an increased incidence of dysbiosis and systemic inflammation. Intervening to restore a healthy balance of gut bacteria has been proven to reduce Inflammation and improve health and wellness. Personalized Interventions based on the Gut Microbiome will have tremendous potential as an additional method for Breast Cancer Prevention and Treatment. | ||
| Keywords | ||
| Breast cancer; Gut Microbiome; estrogen metabolism; inflammation; immune modulation; nutritional factors | ||
|
Supplementary Files
|
||
|
Statistics Article View: 488 PDF Download: 73 |
||
