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Preparation and Characterization of Nano-Antioxidant Via Ionically Cross-Linked Propolis Nanoparticles with Chitosan Polymer as A Carrier | ||
| Basrah Journal of Veterinary Research | ||
| Volume 25, Issue 2, June 2026, Pages 15-29 PDF (834.85 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.23975/bjvr.2026.169076.1291 | ||
| Authors | ||
| Dr.Rashad Fadhil Ghadhban* 1; Abrar Abdulrazaaq2 | ||
| 1physiology, pharmacology and biochemistry Dep. veterinary medicine college Basrah University | ||
| 2UNIVERSITY OF BASRAH/ PHARMACY COLLEGE | ||
| Abstract | ||
| Abstract: This study aimed to preparation and characterization of nano propolis by encapsulating propolis extract with Chitosan (CS) using ionic gelation method to produce Chitosan-propolis Nanoparticles (Cs-Pr NPS). Propolis is well known as antioxidant, anti-inflammatory, but its clinical efficacy is limiting due to poor water solubility, to overcome these challenges, nanoencapsulation technology has been used to enhance its therapeutic efficacy. UV-Vis spectroscopy, FTIR, FESEM, XRD and AFM analysis were applied to confirm success of nano-formulation and structural integrity of nanoparticles. UV-Vis spectroscopy confirms the preservation of biologically active components, as absorption peaks corresponding to flavonoid and phenolic compounds, FTIR showed presence of hydroxyl (-OH) and carbonyl (C=O) functional groups of propolis and nanopropolis, FESEM of nanopropolis show smooth spherical with size between (35-51nm), XRD confirmed the crystalline nature of the Cs-Pr NPs. In addition to AFM confirm well dispersed nanoparticles with spherical morphology and smooth surface. | ||
| Keywords | ||
| Nano propolis; propolis; Antioxidant; Ionic Gelation | ||
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