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Feline Calicivirus: from Genetic Evolutionary and Clinical Diversity to Control Strategies in a Review | ||
| Basrah Journal of Veterinary Research | ||
| Volume 25, Issue 2, June 2026, Pages 206-214 PDF (547.46 K) | ||
| Document Type: Review Paper | ||
| DOI: 10.23975/bjvr.2026.169804.1294 | ||
| Author | ||
| saja Hamza Abdul Aziz* | ||
| University of basrah-college of veterinary medicine | ||
| Abstract | ||
| Abstract Feline calicivirus (FCV) is recognized as one of the most prevalent etiological agents of disease in cats, distinguished by its high transmissibility and a remarkable capacity for immune evasion.Following the acute phase of infection, some cats may persist as chronic carriers or experience recurrent cycles of infection with different or mutated strains, making them a major Clinical manifestations of infection often include upper respiratory tract infections, oral ulcers, and excessive salivation, in addition to gingivitis and stomatitis in other cases. In some forms, may progress to a more severe type known as Virulent Systemic Feline Calicivirus (VSFCV), which is associated with high mortality rates. Because of high transcription polymerase error rates in RNA virus so it has given it a strong ability for genetic adaptation, allowing it to respond quickly to environmental instability.This phenomena allow it to undergo severe genetic and antigenic diversity, leaning in the develoment of new variants that complicate the process of controlling it later. FCV is associated with a wide range of clinical signs, starting from asymptomatic infections and relatively mild oral and respiratory illnesses to severe lameness with or without systemic infections with high mortality rate.It is worth noting that a percentage of cats that recover from acute infection remain infected with chronic infection,and it is believed that continues evolution of the virus within these animals helps it evade the host immune response. Although these chronic cases may represent a minority, they play a pivotal role in the epidemiology and spread of the virus. | ||
| Keywords | ||
| Cat; Feline calicivirus; Review | ||
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