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Evaluation of Efficacy of Empirical Antibiotics Therapy for Burn Patients In Sulaymaniyah Hospital for Burn and Plastic surgery | ||
| Ninevah Journal of Public Health & Nursing | ||
| Articles in Press, Accepted Manuscript, Available Online from 11 August 2026 | ||
| Document Type: Original Article | ||
| DOI: 10.64554/njphn.2026.173051.1018 | ||
| Authors | ||
| Dana Abdilmagid Abdilkarim* ; Arwin Amir Hadi; Azhi Anwar Abdallah; Sahand Kaiwan Rashid | ||
| Branch of Clinical Science, College of Medicine, University Sulaymaniyah | ||
| Abstract | ||
| Background: Adherence to evidence-based antibiotic prescribing protocols is crucial for optimizing outcomes in burn patients, where infections significantly contribute to morbidity and mortality. Objective: To provide antimicrobial susceptibility data for common bacterial pathogens in burn wounds to guide empirical antibiotic selection at Sulaymaniyah Hospital for Burn and Plastic Surgery. Patients and Methods: This retrospective observational study analyzed 132 burn patients with confirmed wound infections at Sulaymaniyah Hospital from January 1, 2021, to December 31, 2023. Inclusion criteria were second- or third-degree burns affecting >10% total body surface area (TBSA) with positive wound cultures. Antibiotic susceptibility was assessed using the Kirby-Bauer disk diffusion method. Results: Staphylococcus aureus (34.1%) was the most common isolate, followed by Pseudomonas aeruginosa (28.8%) and Acinetobacter baumannii (17.4%) (Table 2). Colistin showed 100% susceptibility across Gram-negative isolates, while vancomycin was highly effective against S. aureus (91.8%) (Table 3). Common antibiotics like meropenem (53.2% susceptibility), amikacin (33.3%), and ciprofloxacin (30.6%) demonstrated reduced efficacy. Conclusion: Empirical therapy should prioritize colistin for Gram-negative pathogens and vancomycin for S. aureus, given widespread resistance to conventional agents (30). Strict stewardship is essential to curb multidrug resistance (11). | ||
| Keywords | ||
| antibiotic resistance; empirical therapy; burn wound infection; Staphylococcus aureus; Pseudomonas aeruginosa; colistin; vancomycin | ||
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