Effect of local garlic( Allium sativum)on cholesterol levels and lipoproteins in the rats blood and some other organs.

	Effect of local garlic( Allium sativum)on cholesterol levels and lipoproteins in the rats blood and some other organs.
Journal of Tikrit University For Agriculture Sciences
Article 1, Volume 9, Issue 1, 2009, Pages 40-50
Abstract
This study was carried out by using male albino rats , the animals were divided into five groups .Different levels of local garlic were added to four groups , while the first group with out any additional ration (control diet). The added levels of local garlic were 0.5%,1%,1.5%,and 2% per Kg diet respectively .After feeding the various garlic levels for four weeks the animal were killed. No significant differences were observed (P≤0.01)in the rate of body weight gain , feed intake, feed conversion efficiency between the control ration and the ration containing various levels of garlic. There was significant decrease in serum cholesterol level (P≤0.01) . animal fed on control ration showed the highest level, the lowest level was seen with ration supplemented with 2% local garlic / Kg ration. There was a significant decrease in very low density + low density lipoprotein (VLDL+LDL) concentration in serum but not in high density lipoprotein (HDL). The was significant decrease (P≤0.01) in liver weight , the differences were not significant for spleen and heart weight. The study pointed out the presence of significant decrease (P≤0.01) in percentage of lipids in liver, heart of animals fed on local garlic supplemented ration compared with the control ration, while the differences were not significant for percentage of lipids in spleen and feces . The same could be found in cholesterol level of the above mentioned organs

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