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Histological Changes of Mice Liver Infected With Toxoplasmosis | ||
| Medical Journal of Tikrit | ||
| Article 1, Volume 2, Issue 132, 2016, Pages 103-108 | ||
| Author | ||
| Rana M. R. Kassabbashi | ||
| Abstract | ||
| This study concerned with the effect of toxoplasmosis on the histology of mice liver. Two groups each of 10 mice were examined. Group (I) left as a control while group (II) were those mice inoculated intraperitoneally with placental fluid containing Toxoplasma Gondii parasite to induce the infection. After 10-15 days of inoculation, the livers of the two groups were examined histologically. Results shoed many histological changes in the livers of infected mice, while there were no changes in the livers of the control group. Histologically the livers of the second group shoed the presence of Toxoplasma Gondii tachyzoites and tissue cysts invading the hepatocytes resting between the endothelial cells of the sinusoidal liver capillaries, together with intense inflammatory cellular infiltrate concentrated mainly around the central veins of the liver lobules, with congestion and hemorrhage within the central veins, dilated sinusoidal capillaries were also very obvious with distortion in the shape of the hepatocytes and foamy appearance of those cells. All these changes indicated that the infection with Toxoplasma Gondii parasite could affect all organs in the body especially the liver. | ||
| Keywords | ||
| Histological Changes of Mice Liver Infected With Toxoplasmosis | ||
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