| A case control study carried out over a period of 10 months from October 2001- August 2002 in Al-Kadhmyia Teaching Hospital to evaluate the relationship between serum level of trace elements (Selenium, Zinc, Copper, Iron, Magnesium and Chromium) and idiopathic dilated cardiomyopathy. Twenty nine patients diagnosed as having idiopathic dilated cardiomyopathy, 22 (75.8%) were males and 7 (24.14%) were females and a 29 healthy control, 20 (68.69) males and 9 (31%) females were included in the study. The diagnosis of idiopathic dilated cardiomyopathy based on history, clinical examination, and laboratory tests (blood sugar, renal function test, liver function test. Blood film and thyroid function test), ECG, echocardiography and cardiac catheterization. Serum level trace elements were estimated by atomic absorption spectrophotometer for both patients and control groups. Regarding the mean level of the trace elements under investigation on our study , the comparison of serum selenium of patients with dilated cardiomyopathy with that of normal individuals show significant difference with lower concentration in both male and female patients group ( mean = 59.2,47.4 ) respectively and ( P<0.05 ) , (P<0.01 ) for male and female respectively. The level of Zinc in the serum of patients were lower than that of the control group with significant statistical difference in the male group (P<0.05). A high mean serum copper of the total patients with dilated cardiomyopathy (mean =1.16) were observed in comparison with normal individuals (mean = 1.12) , however no statistical difference between the two group were observed. Iron level estimation revealed higher value in the patients group (mean =0.8), however this difference statistically not significant. Regarding magnesium level, no marked difference between the two groups. No significant difference in the mean serum level of chromium in both groups was detected. However there is a lower serum chromium level in the male patients despite no statistical difference. |