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Renin angiotensin system and cardiovascular risks in patients taking captopril | ||
| Medical Journal of Tikrit | ||
| Article 1, Volume 1, Issue 141, 2012, Pages 36-41 | ||
| Authors | ||
| Mossa M. Marbut; Hassan K. Rajab | ||
| Abstract | ||
| Captopril is an angiotensin converting enzyme (ACE) inhibitors which is the treatment of hypertension & heart failure. Captopril prevent the conversion of angiotensin 1 to II by inhibiting of peptidyl dipeptide carboxy hydrolase enzyme. Fifty seven hypertensive patients taking captopril as a tablet 25 mg twice per day (22 male & 35 women). Each patient had a complete history detailed, physical examination, all patients were interviewed & full medical history was taken. Questionnaires were asked about the presence or absence of headache, palpitation, cough, flushing, chest pain, dysgeusia & tachycardia. Blood pressure & heart rate were measured for each patient each visit. 14 men patients out of 22 hypertensive patients are diagnosed as suffering from palpitation. In hypertensive men, there are no significant differences between group with palpitation & patients without palpitation regarding blood pressure in both systolic & diastolic. Also, there is no significant differences regarding heart rate between group of patients with palpitation & group of patients without palpitation. Palpitations are can be attributed to one of the three main causes. First cause is hyperdynamic circulation which include hypercapnia, pyrexia, thyrotoxicosis, anemia & pregnancy. The second cause is sympathetic overdrive include panic disorders, hypoglycemia, hypoxia, heart failure & mitral valve prolapse. While the third main cause is arrhythmias | ||
| Keywords | ||
| Renin angiotensin system and cardiovascular risks in patients taking captopril | ||
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