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Serum lipid profile in Psoriasis: a controlled study | ||
| Medical Journal of Tikrit | ||
| Article 1, Volume 1, Issue 171, 2012, Pages 38-42 | ||
| Author | ||
| Ahmed Abdul-Aziz Ahmed | ||
| Abstract | ||
| Psoriasis is an inflammatory dermatosis that is characterized with hyperproliferation of keratinocytes and inflammatory infiltration in the epidermis and dermis. The high prevalence of atherosclerosis has been reported in psoriatic patients. High serum lipid level has been suggested in the pathogenesis of this phenomenon. In this study, our purpose was to compare the lipid profile in psoriatic patients with non-affected persons. This study was designed and conducted as a case-control assay with 19 patients in the first group and24 cases as control groups. The lipid profile, including serum level of triglyceride, cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL), were assessed in both groups. The patient group consisted of 19 (6 male and 13 female )and control group consisted of 24cases (11 male and 13 female). The serum triglyceride, and LDL was significantly higher in psoriatic patients (P < 0.05).CONCLUSION: This study, like previous assays, shows that high serum lipid level is significantly more common in psoriasis. This fact may be responsible for higher prevalence of cardiovascular accident in psoriatic patients. It may be useful to do early screening and treatment of hyperlipidaemia in psoriasis to prevent the atherosclerosis and its complications. | ||
| Keywords | ||
| Serum lipid profile in Psoriasis | ||
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