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Acute Transformation In Chronic Myelogenous Leukaemia | ||
| Medical Journal of Tikrit | ||
| Article 1, Volume 1, Issue 131, 2012, Pages 12-17 | ||
| Author | ||
| Alaa Fadhil Alwan | ||
| Abstract | ||
| Fifty-three patients with chronic myeloid leukaemia (CML) were included in this study (25 females & 28 males) and followed-up from October 2003 till October 2005 included for the evidence of acute transformation. Twenty-one patients (39.6%) transformed to acute phase , 16 patients(76.1%) of them transformed during the first 4 years of diagnosis. Fifteen patients (71.4 %) ) transformed to acute myeloid leukaemia and 6 patients (28.6 %) transformed to acute lymphoblastic leukaemia. The mean age was 36 years with range of 16-60 years. The most common presentation of patients experiencing the acute transformation were fever (95%), splenomegaly (66%) and bone pain (57%).The mean survival of acute transformation was 5.3 months | ||
| Keywords | ||
| Acute Transformation In Chronic Myelogenous Leukaemia | ||
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