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Relationship between iron deficiency and gall stones formation | ||
| Medical Journal of Tikrit | ||
| Article 1, Volume 2, Issue 152, 2016, Pages 119-123 | ||
| Authors | ||
| Salim J. Khalaf; Mahdi S. Hamed; Hamid H. Sarhan | ||
| Abstract | ||
| The old axiom that a typical gall stone sufferer is a fat, fertile, female of fifty, is only partially true, as the disease is found in women soon after their first delivery and also in underweight and thin people. So while searching for other parameters, iron deficiency was found to be a new parameter of interest in the etiology of gall stones. The aim of the study was aimed at establishing the role of iron deficiency in the supersaturation of bile with cholesterol and thus formation of gallstone. 50 patients of cholelithiasis, confirmed by ultrasonography (USG) were divided into anemic and non-anemic groups, based on serum iron levels. Serum cholesterol and gall bladder bile cholesterol of both the groups were estimated. Data amongst the two groups were subjected to statistical analysis using students t-test. The P -value <0.05 was considered significant. Total serum cholesterol was not different in gall stone formers from that of the general population. Gall bladder bile cholesterol was significantly higher in anemic, than in non-anemic individuals. The present study conclude that low serum iron levels lead to bile supersaturation with respect to cholesterol, which leads to gallstone formation | ||
| Keywords | ||
| Relationship between iron deficiency and gall stones formation | ||
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