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Treatment of candidiasis by Ceratonia Siliqua | ||
| Medical Journal of Tikrit | ||
| Article 1, Volume 2, Issue 152, 2016, Pages 181-185 | ||
| Authors | ||
| Al-Taie T.S; Haidar M. Jawad | ||
| Abstract | ||
| Candida albicans is the most common fungal pathogen isolated from the oral cavity. The aim of this study was to evaluate the anti fungal activity of the Ceratonia siliqua extract and to observe the effectiveness of the extract in the treatment of oral candidiasis. In vitro study; culture for candidal species was conducted in the lab. identified, and inoculated the agar plate. Different concentrations (1,5,10mg/ml) of Ceratonia siliqua aqueous extract was added and the inhibition zones were recorded after 24 hours of incubation. In vivo study; was conducted in a single-blind technique. Twenty- two patients with oral candidiasis (9 female, 13 males, age range 1 month-60 yrs) were treated by a suspension of 10 mg /ml Ceratonia siliqua extract, applied topically, 4 times daily for 5 days. In vitro results showed no growth of Candida albicans in the agar plate, with different concentrations 1,5,10 mg/ml of Ceratonia siliqua extract while the in vivo study revealed that 18 patients were cured , and 4 patients got partial cure (p < 0.05 ).Our results support the potential and effectiveness of Ceratonia siliqua 10 mg/ml suspension in the treatment of candidiasis with lack of side effects | ||
| Keywords | ||
| Treatment of candidiasis by Ceratonia Siliqua | ||
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