The Correlation between Concentration of Atlatoxins andOchratoxin A and Tumor Patienl·s Cases in Nineveh province

Al-Wezy, K.M.; Ahmed, M.M.; K.M.Thalij,

	The Correlation between Concentration of Atlatoxins andOchratoxin A and Tumor Patienl·s Cases in Nineveh province
Tikret Journal of Pharmaceutical Sciences
Article 1, Volume 6, Issue 2, 2010, Pages 94-101
Authors
K.M. Al-Wezy; M.M. Ahmed;
Abstract
This study was conducted to investigate the correlation between occurrence of AflatoxinsBl (AFBI), MJ (Al!Ml), Aflatoxicol, nnd Ochratoxin A (OA), and tumor patients inKineveh province. Blood, urine aad tissue:> samples m:re taken fmm 33 tumor patients atliver and kidney organs, and 18 li3l1lples from henlthy volunteer's peoples to estimated thepresence ami concentration of AFBI, AFMl, Aflatoxicol, and OA contents. 11 had beenfound thAt the AI'B I, AFM l, and OA at a high percentage in blood samples frout patientsgroup at 42.4, 45.5, and 42.4% respectively and high range concemrations 4.5 to 13.1,9.4 to 31.6, and 1.02 to 8.6 ngll 00 ml of blood respectively, compared with the abovemycotoxins presence in sam" samples from boolrhy group. On the other hand there wa~ ahighly pen:entage for occurrence and concentrations of AFBI, AFMI, aflatoxicol, andOA in urine samples from patients group (54.5, 66.7, 60.6 and 42.4 % respectively andtbcconcenlrations at 5.210 25.1, l0.7to J6.8, 7.2 to 20.3 1111d 9.2to 33.7 ng/100 ml ofurine respectively when compared with the same samples from healthy group.Furthermore, found that u high concentration of AFBI, AFMl, and OA in the liver andlcidm:y samples that token from tumor patients group. The resultS was Cl'rrtr""! !1-~strongly correlation between level •x:curreoce and concentration of n>yctoxins type andthe tumor cases in contributors peoples.

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